UniProtKB - B0VZ56 (B0VZ56_CULQU)
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Protein
Superoxide dismutase [Cu-Zn]
Gene
6030958
Organism
Culex quinquefasciatus (Southern house mosquito) (Culex pungens)
Status
Functioni
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation
Catalytic activityi
2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation
Cofactori
Protein has several cofactor binding sites:- Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
- Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- superoxide dismutase activity Source: UniProtKB-EC
Keywordsi
Molecular function | OxidoreductaseUniRule annotation |
Ligand | CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:6030958Imported ORF Names:CpipJ_CPIJ000146Imported |
Organismi | Culex quinquefasciatus (Southern house mosquito) (Culex pungens)Imported |
Taxonomic identifieri | 7176 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Culicini › Culex › Culex › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_5011407379 | 20 – 173 | Superoxide dismutase [Cu-Zn]Sequence analysisAdd BLAST | 154 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 170 | Sod_CuInterPro annotationAdd BLAST | 137 |
Sequence similaritiesi
Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG0441. Eukaryota. COG2032. LUCA. |
HOGENOMi | HOG000263447. |
InParanoidi | B0VZ56. |
KOi | K04565. |
OMAi | HKGDIGN. |
OrthoDBi | EOG091G0OG2. |
PhylomeDBi | B0VZ56. |
Family and domain databases
CDDi | cd00305. Cu-Zn_Superoxide_Dismutase. 1 hit. |
Gene3Di | 2.60.40.200. 1 hit. |
InterProi | View protein in InterPro IPR036423. SOD-like_Cu/Zn_dom_sf. IPR024134. SOD_Cu/Zn_/chaperone. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. |
PANTHERi | PTHR10003. PTHR10003. 1 hit. |
Pfami | View protein in Pfam PF00080. Sod_Cu. 1 hit. |
PRINTSi | PR00068. CUZNDISMTASE. |
SUPFAMi | SSF49329. SSF49329. 1 hit. |
PROSITEi | View protein in PROSITE PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
B0VZ56-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKVLIVLAIF GCSTLLVNAD QAKKAIVFLQ STAGVVGNVT LSQPSCTEPV
60 70 80 90 100
FIEVSVIGLT PGKHGFHIHE KGDLSDGCAS TGGHYNPDKV SHGAPNDQVR
110 120 130 140 150
HVGDLGNILA DEHGIAKTSF SDTVVSLYGS RSVLGRGIVI HAEIDDLGKT
160 170
NHPDSLKTGN AGGRVACGVI GVL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS231813 Genomic DNA. Translation: EDS25769.1. |
RefSeqi | XP_001841816.1. XM_001841764.1. |
UniGenei | Cpi.1106. |
Genome annotation databases
EnsemblMetazoai | CPIJ000146-RA; CPIJ000146-PA; CPIJ000146. |
GeneIDi | 6030958. |
KEGGi | cqu:CpipJ_CPIJ000146. |
VectorBasei | CPIJ000146-RA; CPIJ000146-PA; CPIJ000146. |
Similar proteinsi
Entry informationi
Entry namei | B0VZ56_CULQU | |
Accessioni | B0VZ56Primary (citable) accession number: B0VZ56 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 8, 2008 |
Last sequence update: | April 8, 2008 | |
Last modified: | March 28, 2018 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |