Reviewed,
UniProtKB/Swiss-Prot B0VUX1 (QUEF_ACIBS)
Last modified
February 9, 2010.
Version 23.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: NADPH-dependent 7-cyano-7-deazaguanine reductase EC=1.7.1.13 Alternative name(s): 7-cyano-7-carbaguanine reductase PreQ(0) reductase NADPH-dependent nitrile oxidoreductase | ||||
| Gene names |
| ||||
| Organism | Acinetobacter baumannii (strain SDF) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 509170 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter |
Protein attributes
| Sequence length | 270 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00817 |
| Catalytic activity | 7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00817 |
| Pathway | tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00817 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00817. |
| Sequence similarities | Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Queuosine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW queuosine biosynthetic processInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor Inferred from electronic annotation. Source: HAMAP queuine synthase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 270 | 270 | NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00817 | PRO_1000193208 | |||
Sequences
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References
| [1] | "Comparative analysis of Acinetobacters: three genomes for three lifestyles." Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S. PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CU468230 Genomic DNA. Translation: CAP00563.1. |
| RefSeq | YP_001706701.1. |
3D structure databases | |
| SMR | B0VUX1. Positions 14-270. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 5984708. |
| GenomeReviews | Gene locus ABSDF1213 in contig CU468230_GR. |
| KEGG | abm:ABSDF1213. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG289139. |
| OMA | INPFRSN. |
Family and domain databases | |
| HAMAP | MF_00817. QueF_type2. [Tree] |
| InterPro | IPR016428. CN_OxRdtase_NADPH-dep_YqcD. IPR020602. GTP_CycHdrlase_I/CN_OxRdtase. [Graphical view] |
| Pfam | PF01227. GTP_cyclohydroI. 1 hit. [Graphical view] |
| PIRSF | PIRSF004750. Nitrile_oxidored_YqcD_prd. 1 hit. |
| TIGRFAMs | TIGR03138. QueF. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | QUEF_ACIBS | ||||||||
| Accession | Primary (citable) accession number: B0VUX1 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


