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B0VTE3 (ARGB_ACIBS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetylglutamate kinase

EC=2.7.2.8
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK
Gene names
Name:argB
Ordered Locus Names:ABSDF2548
OrganismAcinetobacter baumannii (strain SDF) [Complete proteome] [HAMAP]
Taxonomic identifier509170 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B

Subcellular location

Cytoplasm By similarity HAMAP MF_00082_B.

Sequence similarities

Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetylglutamate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302Acetylglutamate kinase HAMAP MF_00082_B
PRO_1000092842

Regions

Region68 – 692Substrate binding By similarity

Sites

Binding site901Substrate By similarity
Binding site1941Substrate By similarity
Site331Transition state stabilizer By similarity
Site2541Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
B0VTE3 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: E8C9B715C057FED5

FASTA30232,293
        10         20         30         40         50         60 
MPQDQHLGVD KAKILIEALP YIQRFSGKTL VVKYGGNAMT DPELESSFAR DIVLLKTVGL 

        70         80         90        100        110        120 
NPIVVHGGGP QVDSFLKQLG RESDRIDGMR VTDEATMEVV EMVLGGSVNK SIVNLINKHG 

       130        140        150        160        170        180 
GRAIGLTGQD GNLLRARKLL MEKQEEDGSI KHIDLGMVGE VTGVKTDVLE MFTQSDFIPV 

       190        200        210        220        230        240 
IAPLGVDEKG NTYNINADLV AGKVAEALGA EKLILLTNIS GVLDENKNLL TGLTTQEVDR 

       250        260        270        280        290        300 
LIETGVIYGG MIPKVGCALD AVKGGVVSAH IVDGRVPHAT LLEIFTDHGV GTLISNRTQT 


TH 

« Hide

References

[1]"Comparative analysis of Acinetobacters: three genomes for three lifestyles."
Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S.
PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SDF.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU468230 Genomic DNA. Translation: CAP01858.1.
RefSeqYP_001707773.1. NC_010400.1.

3D structure databases

ProteinModelPortalB0VTE3.
SMRB0VTE3. Positions 12-297.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0VTE3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5985697.
GenomeReviewsGene locus ABSDF2548 in contig CU468230_GR.
KEGGabm:ABSDF2548.
PATRIC20735819. VBIAciBau88365_2416.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG497643.
OMAGGNAMID.
ProtClustDBPRK00942.

Family and domain databases

HAMAPMF_00082_B. ArgB_B.
[Tree]
InterProIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00930.
PfamPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000728. NAGK. 1 hit.
SUPFAMSSF53633. Aa_kinase. 1 hit.
TIGRFAMsTIGR00761. ArgB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARGB_ACIBS
AccessionPrimary (citable) accession number: B0VTE3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families