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Protein

S-adenosylmethionine:tRNA ribosyltransferase-isomerase

Gene

queA

Organism
Acinetobacter baumannii (strain SDF)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.UniRule annotation

Pathwayi: tRNA-queuosine biosynthesis

This protein is involved in the pathway tRNA-queuosine biosynthesis, which is part of tRNA modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway tRNA-queuosine biosynthesis and in tRNA modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processQueuosine biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00392

Names & Taxonomyi

Protein namesi
Recommended name:
S-adenosylmethionine:tRNA ribosyltransferase-isomeraseUniRule annotation (EC:2.4.99.17UniRule annotation)
Alternative name(s):
Queuosine biosynthesis protein QueAUniRule annotation
Gene namesi
Name:queAUniRule annotation
Ordered Locus Names:ABSDF0521
OrganismiAcinetobacter baumannii (strain SDF)
Taxonomic identifieri509170 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
Proteomesi
  • UP000001741 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000947421 – 351S-adenosylmethionine:tRNA ribosyltransferase-isomeraseAdd BLAST351

Proteomic databases

PRIDEiB0VRB1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0VRB1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the QueA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004401
KOiK07568
OMAiYSYGDGM

Family and domain databases

HAMAPiMF_00113 QueA, 1 hit
InterProiView protein in InterPro
IPR003699 QueA
IPR036100 QueA_sf
PANTHERiPTHR30307 PTHR30307, 1 hit
PfamiView protein in Pfam
PF02547 Queuosine_synth, 1 hit
SUPFAMiSSF111337 SSF111337, 1 hit
TIGRFAMsiTIGR00113 queA, 1 hit

Sequencei

Sequence statusi: Complete.

B0VRB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLSDFSFEL PDELIARYPL ETRSASRLLH LDAKGQYHDH MFTDIIDLFE
60 70 80 90 100
EGDLLVLNDT KVMKARLKGK RTTGGAIEIL VERMPNHTTA YCHIKASNSP
110 120 130 140 150
KAGAELFVGA DNIPVIVRGR HENLFVVEFS QPILPVLEQY GQLPIPPYFN
160 170 180 190 200
REAEEIDTER YQTVFHNPEK IASVAAPTAS LHFDEELLAK LDQKGVKKTF
210 220 230 240 250
VTLHVGAGTF MPVRTDDITN HVMHSEWCDV PQETIDLILA TKARGNKVIA
260 270 280 290 300
VGTTATRALE SAAQAHGGKI AAWTGDTQIF IYPGYEFCIV DRLITNFHLP
310 320 330 340 350
ESTLLMLVSA LSNRENILAA YEHAVKDRYH FFSYGDAMLI DKLEVLKLKL

G
Length:351
Mass (Da):39,347
Last modified:April 8, 2008 - v1
Checksum:i65FEB79BDD405A32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468230 Genomic DNA Translation: CAO99905.1

Genome annotation databases

EnsemblBacteriaiCAO99905; CAO99905; ABSDF0521
KEGGiabm:ABSDF0521

Entry informationi

Entry nameiQUEA_ACIBS
AccessioniPrimary (citable) accession number: B0VRB1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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