B0VR86 (MSRB_ACIBS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	ABSDF2180

Organism

Acinetobacter baumannii (strain SDF) [Complete proteome] [HAMAP]

Taxonomic identifier

509170 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter › Acinetobacter calcoaceticus/baumannii complex

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity.
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 139	139	Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400		PRO_1000145346
Sites
	Active site	119	1	Nucleophile By similarity
	Metal binding	47	1	Zinc By similarity
	Metal binding	50	1	Zinc By similarity
	Metal binding	96	1	Zinc By similarity
	Metal binding	99	1	Zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0VR86 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 5B583F9B4E5C8D86	FASTA	139	15,837
	10 20 30 40 50 60 MGKVNKTDRE WQRELSPEEY RITRQKGTEP AFTGQYWNTK QHGTYVCRCC GAELFSSDAK 70 80 90 100 110 120 YDSGCGWPSF FRPLNGSVID EHEDLTHGMV RTEIVCHDCE AHLGHVFEDG PQPTGLRYCV 130 NSASLQLKTQ EKNDEGTYP

References

[1]

"Comparative analysis of Acinetobacters: three genomes for three lifestyles." Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S. PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SDF.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU468230 Genomic DNA. Translation: CAP01505.1.
RefSeq	YP_001707473.1. NC_010400.1.
3D structure databases
ProteinModelPortal	B0VR86.
SMR	B0VR86. Positions 3-128.
ModBase	Search...
Protein-protein interaction databases
STRING	B0VR86.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5986835.
GenomeReviews	Gene locus ABSDF2180 in contig CU468230_GR.
KEGG	abm:ABSDF2180.
PATRIC	20735127. VBIAciBau88365_2073.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG715255.
OMA	APLFRSD.
ProtClustDB	CLSK707445.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_ACIBS

Accession

Primary (citable) accession number: B0VR86

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program