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B0VNL8

- DEF_ACIBS

UniProt

B0VNL8 - DEF_ACIBS

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Protein

Peptide deformylase

Gene

def

Organism
Acinetobacter baumannii (strain SDF)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.UniRule annotation

Catalytic activityi

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide.UniRule annotation

Cofactori

Fe2+UniRule annotationNote: Binds 1 Fe(2+) ion.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi92 – 921IronUniRule annotation
Metal bindingi134 – 1341IronUniRule annotation
Active sitei135 – 1351UniRule annotation
Metal bindingi138 – 1381IronUniRule annotation

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. peptide deformylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide deformylaseUniRule annotation (EC:3.5.1.88UniRule annotation)
Short name:
PDFUniRule annotation
Alternative name(s):
Polypeptide deformylaseUniRule annotation
Gene namesi
Name:defUniRule annotation
Ordered Locus Names:ABSDF0185
OrganismiAcinetobacter baumannii (strain SDF)
Taxonomic identifieri509170 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000001741: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 176176Peptide deformylasePRO_1000097291Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi509170.ABSDF0185.

Structurei

3D structure databases

ProteinModelPortaliB0VNL8.
SMRiB0VNL8. Positions 1-167.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the polypeptide deformylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0242.
HOGENOMiHOG000243509.
KOiK01462.
OMAiTFIDNMF.
OrthoDBiEOG664CMF.

Family and domain databases

Gene3Di3.90.45.10. 1 hit.
HAMAPiMF_00163. Pep_deformylase.
InterProiIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
PANTHERiPTHR10458. PTHR10458. 1 hit.
PfamiPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFiPIRSF004749. Pep_def. 1 hit.
PRINTSiPR01576. PDEFORMYLASE.
SUPFAMiSSF56420. SSF56420. 1 hit.
TIGRFAMsiTIGR00079. pept_deformyl. 1 hit.

Sequencei

Sequence statusi: Complete.

B0VNL8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALLPILSFP DPRLRTIAKP VEEVTDEIRQ LAADMFETMY AAPGIGLAAS
60 70 80 90 100
QVDRHIQLIV MDLSESKDEP MVFINPKVTP LTEETQPYEE GCLSVPQIYD
110 120 130 140 150
KVDRPSRVKI EAINLEGQAF EIEADGLLAV CIQHEMDHLN GKLFVDYLSP
160 170
LKRQRVREKV EKIVRQRERE KVAVKR
Length:176
Mass (Da):20,095
Last modified:April 8, 2008 - v1
Checksum:iCBDCA96B5FDA36D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468230 Genomic DNA. Translation: CAO99588.1.
RefSeqiWP_001196540.1. NC_010400.1.
YP_001705913.1. NC_010400.1.

Genome annotation databases

EnsemblBacteriaiCAO99588; CAO99588; ABSDF0185.
GeneIDi5984020.
KEGGiabm:ABSDF0185.
PATRICi20731331. VBIAciBau88365_0219.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468230 Genomic DNA. Translation: CAO99588.1 .
RefSeqi WP_001196540.1. NC_010400.1.
YP_001705913.1. NC_010400.1.

3D structure databases

ProteinModelPortali B0VNL8.
SMRi B0VNL8. Positions 1-167.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 509170.ABSDF0185.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAO99588 ; CAO99588 ; ABSDF0185 .
GeneIDi 5984020.
KEGGi abm:ABSDF0185.
PATRICi 20731331. VBIAciBau88365_0219.

Phylogenomic databases

eggNOGi COG0242.
HOGENOMi HOG000243509.
KOi K01462.
OMAi TFIDNMF.
OrthoDBi EOG664CMF.

Family and domain databases

Gene3Di 3.90.45.10. 1 hit.
HAMAPi MF_00163. Pep_deformylase.
InterProi IPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view ]
PANTHERi PTHR10458. PTHR10458. 1 hit.
Pfami PF01327. Pep_deformylase. 1 hit.
[Graphical view ]
PIRSFi PIRSF004749. Pep_def. 1 hit.
PRINTSi PR01576. PDEFORMYLASE.
SUPFAMi SSF56420. SSF56420. 1 hit.
TIGRFAMsi TIGR00079. pept_deformyl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SDF.

Entry informationi

Entry nameiDEF_ACIBS
AccessioniPrimary (citable) accession number: B0VNL8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: November 26, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3