B0VNF5 (DADA_ACIBS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	ABSDF0116

Organism

Acinetobacter baumannii (strain SDF) [Complete proteome] [HAMAP]

Taxonomic identifier

509170 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter › Acinetobacter calcoaceticus/baumannii complex

Protein attributes

Sequence length	421 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 421	421	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_1000138636
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	B0VNF5 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 40C2D6C36E648411	FASTA	421	46,421
	10 20 30 40 50 60 MRVIVLGSGV IGVASAYYLA RQGAEVTVLD RQSGPAEETS FGNAGQISPG YSTPWAAPGI 70 80 90 100 110 120 PFKAVKWMFQ HHAPLAINLD GSMWQLQWMA QMLKNCNPQS YAVNKERMMR VAEYSRDCLR 130 140 150 160 170 180 ELRKDTGIHY ENRAKGTLQL FRKEAQMEAV QRDISVLEEC GVSYELLNGN ELGRVEPALA 190 200 210 220 230 240 NAQDKLVGGL HLPNDETGDC YLFTNALAQI AKELGVNFQF NQNVEKLIVE GDQIKGVQVN 250 260 270 280 290 300 GKVLTADRYV LAFGSYSRDF LKPLDLQLPV YPVKGYSLTI PIVAPAFAPQ STVLDETYKI 310 320 330 340 350 360 AITRFDQRIR VGGMAELSGF NLGLNEDRHA TLQMVTQDLF PGGDMEQASF WTGLRPMTPD 370 380 390 400 410 420 STPIIGATRF KNLFLNTGHG TLGWTMACGS GKLISDIVLN HKTDISTDGL SIQRYSHAHA A

References

[1]

"Comparative analysis of Acinetobacters: three genomes for three lifestyles." Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S. PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SDF.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU468230 Genomic DNA. Translation: CAO99525.1.
RefSeq	YP_001705862.1. NC_010400.1.
3D structure databases
ProteinModelPortal	B0VNF5.
ModBase	Search...
Protein-protein interaction databases
STRING	B0VNF5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5986979.
GenomeReviews	Gene locus ABSDF0116 in contig CU468230_GR.
KEGG	abm:ABSDF0116.
PATRIC	20731200. VBIAciBau88365_0156.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG729204.
OMA	VDRQPAV.
ProtClustDB	PRK00711.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_ACIBS

Accession

Primary (citable) accession number: B0VNF5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program