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B0VMJ8

- B0VMJ8_ACIBS

UniProt

B0VMJ8 - B0VMJ8_ACIBS

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Protein

Aquaporin Z

Gene

aqpZ

Organism
Acinetobacter baumannii (strain SDF)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei19 – 191Involved in tetramerization or stability of the tetramerUniRule annotation
Sitei42 – 421Selectivity filterUniRule annotation
Sitei172 – 1721Selectivity filterUniRule annotation
Sitei181 – 1811Selectivity filterUniRule annotation
Sitei187 – 1871Selectivity filterUniRule annotation

GO - Molecular functioni

  1. water channel activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Aquaporin ZUniRule annotation
Gene namesi
Name:aqpZUniRule annotationImported
Ordered Locus Names:ABSDF3343Imported
OrganismiAcinetobacter baumannii (strain SDF)Imported
Taxonomic identifieri509170 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000001741: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalUniRule annotationAdd
BLAST
Transmembranei22 – 4221HelicalUniRule annotationAdd
BLAST
Transmembranei81 – 10121HelicalUniRule annotationAdd
BLAST
Transmembranei127 – 14721HelicalUniRule annotationAdd
BLAST
Transmembranei158 – 17821HelicalUniRule annotationAdd
BLAST
Transmembranei200 – 22021HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi509170.ABSDF3343.

Structurei

3D structure databases

ProteinModelPortaliB0VMJ8.
SMRiB0VMJ8. Positions 3-229.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi62 – 643NPA 1UniRule annotation
Motifi184 – 1863NPA 2UniRule annotation

Domaini

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).UniRule annotation

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

Keywords - Domaini

RepeatUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG0580.
HOGENOMiHOG000288286.
KOiK06188.
OMAiMPIIGGI.
OrthoDBiEOG6GFGN7.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
HAMAPiMF_01146. Aquaporin_Z.
InterProiIPR023271. Aquaporin-like.
IPR023743. Aquaporin_Z.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0VMJ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKYFAEFLG TFWLVFGGCG SAVLAAAFPE LGIGFAGVAL AFGLTVLTGA
60 70 80 90 100
YALGHISGGH FNPAVSVGLW VGGRFDVKDL IPYIVAQVVG ATAAAFVLYI
110 120 130 140 150
IAQGQAGFSG VGGFAANGFG DLSPNKFGLG SAFIIEVVLT AFFLIIILGA
160 170 180 190 200
TDRRAPAGFA PIAIGLGLTL IHLISIPVTN TSVNPARSTG VAFFAETAAL
210 220
SQLWLFWVAP ILGAVIGAII YKVVAGDKD
Length:229
Mass (Da):23,443
Last modified:April 8, 2008 - v1
Checksum:iE6CB05D97950F795
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468230 Genomic DNA. Translation: CAP02612.1.
RefSeqiYP_001708412.1. NC_010400.1.

Genome annotation databases

EnsemblBacteriaiCAP02612; CAP02612; ABSDF3343.
GeneIDi5986174.
KEGGiabm:ABSDF3343.
PATRICi20737366. VBIAciBau88365_3158.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468230 Genomic DNA. Translation: CAP02612.1 .
RefSeqi YP_001708412.1. NC_010400.1.

3D structure databases

ProteinModelPortali B0VMJ8.
SMRi B0VMJ8. Positions 3-229.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 509170.ABSDF3343.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP02612 ; CAP02612 ; ABSDF3343 .
GeneIDi 5986174.
KEGGi abm:ABSDF3343.
PATRICi 20737366. VBIAciBau88365_3158.

Phylogenomic databases

eggNOGi COG0580.
HOGENOMi HOG000288286.
KOi K06188.
OMAi MPIIGGI.
OrthoDBi EOG6GFGN7.

Family and domain databases

Gene3Di 1.20.1080.10. 1 hit.
HAMAPi MF_01146. Aquaporin_Z.
InterProi IPR023271. Aquaporin-like.
IPR023743. Aquaporin_Z.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view ]
PANTHERi PTHR19139. PTHR19139. 1 hit.
Pfami PF00230. MIP. 1 hit.
[Graphical view ]
PRINTSi PR00783. MINTRINSICP.
SUPFAMi SSF81338. SSF81338. 1 hit.
TIGRFAMsi TIGR00861. MIP. 1 hit.
PROSITEi PS00221. MIP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SDFImported.

Entry informationi

Entry nameiB0VMJ8_ACIBS
AccessioniPrimary (citable) accession number: B0VMJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3