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B0VMJ8 (B0VMJ8_ACIBS) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length229 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity By similarity. HAMAP-Rule MF_01146

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01146

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01146.

Domain

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA) By similarity. HAMAP-Rule MF_01146

Sequence similarities

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification] HAMAP-Rule MF_01146

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane1 – 2121Helical; By similarity HAMAP-Rule MF_01146
Transmembrane22 – 4221Helical; By similarity HAMAP-Rule MF_01146
Transmembrane81 – 10121Helical; By similarity HAMAP-Rule MF_01146
Transmembrane127 – 14721Helical; By similarity HAMAP-Rule MF_01146
Transmembrane158 – 17821Helical; By similarity HAMAP-Rule MF_01146
Transmembrane200 – 22021Helical; By similarity HAMAP-Rule MF_01146
Motif62 – 643NPA 1 By similarity HAMAP-Rule MF_01146
Motif184 – 1863NPA 2 By similarity HAMAP-Rule MF_01146

Sites

Site191Involved in tetramerization or stability of the tetramer By similarity HAMAP-Rule MF_01146
Site421Selectivity filter By similarity HAMAP-Rule MF_01146
Site1721Selectivity filter By similarity HAMAP-Rule MF_01146
Site1811Selectivity filter By similarity HAMAP-Rule MF_01146
Site1871Selectivity filter By similarity HAMAP-Rule MF_01146

Sequences

Sequence LengthMass (Da)Tools
B0VMJ8 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: E6CB05D97950F795

FASTA22923,443
        10         20         30         40         50         60 
MNKYFAEFLG TFWLVFGGCG SAVLAAAFPE LGIGFAGVAL AFGLTVLTGA YALGHISGGH 

        70         80         90        100        110        120 
FNPAVSVGLW VGGRFDVKDL IPYIVAQVVG ATAAAFVLYI IAQGQAGFSG VGGFAANGFG 

       130        140        150        160        170        180 
DLSPNKFGLG SAFIIEVVLT AFFLIIILGA TDRRAPAGFA PIAIGLGLTL IHLISIPVTN 

       190        200        210        220 
TSVNPARSTG VAFFAETAAL SQLWLFWVAP ILGAVIGAII YKVVAGDKD 

« Hide

References

[1]"Comparative analysis of Acinetobacters: three genomes for three lifestyles."
Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S.
PLoS ONE 3:E1805-E1805(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SDF EMBL CAP02612.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU468230 Genomic DNA. Translation: CAP02612.1.
RefSeqYP_001708412.1. NC_010400.1.

3D structure databases

ProteinModelPortalB0VMJ8.
SMRB0VMJ8. Positions 3-229.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING509170.ABSDF3343.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP02612; CAP02612; ABSDF3343.
GeneID5986174.
KEGGabm:ABSDF3343.
PATRIC20737366. VBIAciBau88365_3158.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0580.
HOGENOMHOG000288286.
KOK06188.
OMAMPIIGGI.
OrthoDBEOG6GFGN7.

Family and domain databases

Gene3D1.20.1080.10. 1 hit.
HAMAPMF_01146. Aquaporin_Z.
InterProIPR023271. Aquaporin-like.
IPR023743. Aquaporin_Z.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERPTHR19139. PTHR19139. 1 hit.
PfamPF00230. MIP. 1 hit.
[Graphical view]
PRINTSPR00783. MINTRINSICP.
SUPFAMSSF81338. SSF81338. 1 hit.
TIGRFAMsTIGR00861. MIP. 1 hit.
PROSITEPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0VMJ8_ACIBS
AccessionPrimary (citable) accession number: B0VMJ8
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)