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B0VMJ8

- B0VMJ8_ACIBS

UniProt

B0VMJ8 - B0VMJ8_ACIBS

Protein

Aquaporin Z

Gene

aqpZ

Organism
Acinetobacter baumannii (strain SDF)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei19 – 191Involved in tetramerization or stability of the tetramerUniRule annotation
    Sitei42 – 421Selectivity filterUniRule annotation
    Sitei172 – 1721Selectivity filterUniRule annotation
    Sitei181 – 1811Selectivity filterUniRule annotation
    Sitei187 – 1871Selectivity filterUniRule annotation

    GO - Molecular functioni

    1. water channel activity Source: UniProtKB-HAMAP

    Keywords - Biological processi

    TransportUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aquaporin ZUniRule annotation
    Gene namesi
    Name:aqpZUniRule annotationImported
    Ordered Locus Names:ABSDF3343Imported
    OrganismiAcinetobacter baumannii (strain SDF)Imported
    Taxonomic identifieri509170 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
    ProteomesiUP000001741: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membraneUniRule annotation, Cell membrane, Membrane

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi509170.ABSDF3343.

    Structurei

    3D structure databases

    ProteinModelPortaliB0VMJ8.
    SMRiB0VMJ8. Positions 3-229.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1 – 2121Helical;UniRule annotationAdd
    BLAST
    Transmembranei22 – 4221Helical;UniRule annotationAdd
    BLAST
    Transmembranei81 – 10121Helical;UniRule annotationAdd
    BLAST
    Transmembranei127 – 14721Helical;UniRule annotationAdd
    BLAST
    Transmembranei158 – 17821Helical;UniRule annotationAdd
    BLAST
    Transmembranei200 – 22021Helical;UniRule annotationAdd
    BLAST

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi62 – 643NPA 1UniRule annotation
    Motifi184 – 1863NPA 2UniRule annotation

    Domaini

    Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).UniRule annotation

    Sequence similaritiesi

    Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

    Keywords - Domaini

    RepeatUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    eggNOGiCOG0580.
    HOGENOMiHOG000288286.
    KOiK06188.
    OMAiMPIIGGI.
    OrthoDBiEOG6GFGN7.

    Family and domain databases

    Gene3Di1.20.1080.10. 1 hit.
    HAMAPiMF_01146. Aquaporin_Z.
    InterProiIPR023271. Aquaporin-like.
    IPR023743. Aquaporin_Z.
    IPR000425. MIP.
    IPR022357. MIP_CS.
    [Graphical view]
    PANTHERiPTHR19139. PTHR19139. 1 hit.
    PfamiPF00230. MIP. 1 hit.
    [Graphical view]
    PRINTSiPR00783. MINTRINSICP.
    SUPFAMiSSF81338. SSF81338. 1 hit.
    TIGRFAMsiTIGR00861. MIP. 1 hit.
    PROSITEiPS00221. MIP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0VMJ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKYFAEFLG TFWLVFGGCG SAVLAAAFPE LGIGFAGVAL AFGLTVLTGA    50
    YALGHISGGH FNPAVSVGLW VGGRFDVKDL IPYIVAQVVG ATAAAFVLYI 100
    IAQGQAGFSG VGGFAANGFG DLSPNKFGLG SAFIIEVVLT AFFLIIILGA 150
    TDRRAPAGFA PIAIGLGLTL IHLISIPVTN TSVNPARSTG VAFFAETAAL 200
    SQLWLFWVAP ILGAVIGAII YKVVAGDKD 229
    Length:229
    Mass (Da):23,443
    Last modified:April 8, 2008 - v1
    Checksum:iE6CB05D97950F795
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU468230 Genomic DNA. Translation: CAP02612.1.
    RefSeqiYP_001708412.1. NC_010400.1.

    Genome annotation databases

    EnsemblBacteriaiCAP02612; CAP02612; ABSDF3343.
    GeneIDi5986174.
    KEGGiabm:ABSDF3343.
    PATRICi20737366. VBIAciBau88365_3158.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU468230 Genomic DNA. Translation: CAP02612.1 .
    RefSeqi YP_001708412.1. NC_010400.1.

    3D structure databases

    ProteinModelPortali B0VMJ8.
    SMRi B0VMJ8. Positions 3-229.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 509170.ABSDF3343.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAP02612 ; CAP02612 ; ABSDF3343 .
    GeneIDi 5986174.
    KEGGi abm:ABSDF3343.
    PATRICi 20737366. VBIAciBau88365_3158.

    Phylogenomic databases

    eggNOGi COG0580.
    HOGENOMi HOG000288286.
    KOi K06188.
    OMAi MPIIGGI.
    OrthoDBi EOG6GFGN7.

    Family and domain databases

    Gene3Di 1.20.1080.10. 1 hit.
    HAMAPi MF_01146. Aquaporin_Z.
    InterProi IPR023271. Aquaporin-like.
    IPR023743. Aquaporin_Z.
    IPR000425. MIP.
    IPR022357. MIP_CS.
    [Graphical view ]
    PANTHERi PTHR19139. PTHR19139. 1 hit.
    Pfami PF00230. MIP. 1 hit.
    [Graphical view ]
    PRINTSi PR00783. MINTRINSICP.
    SUPFAMi SSF81338. SSF81338. 1 hit.
    TIGRFAMsi TIGR00861. MIP. 1 hit.
    PROSITEi PS00221. MIP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SDFImported.

    Entry informationi

    Entry nameiB0VMJ8_ACIBS
    AccessioniPrimary (citable) accession number: B0VMJ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3