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B0VLU2

- IF2_ACIBS

UniProt

B0VLU2 - IF2_ACIBS

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Acinetobacter baumannii (strain SDF)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi408 – 4158GTPUniRule annotation
    Nucleotide bindingi454 – 4585GTPUniRule annotation
    Nucleotide bindingi508 – 5114GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:ABSDF3180
    OrganismiAcinetobacter baumannii (strain SDF)
    Taxonomic identifieri509170 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
    ProteomesiUP000001741: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 899899Translation initiation factor IF-2PRO_1000093750Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi509170.ABSDF3180.

    Structurei

    3D structure databases

    ProteinModelPortaliB0VLU2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini399 – 568170tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni408 – 4158G1By similarity
    Regioni433 – 4375G2By similarity
    Regioni454 – 4574G3By similarity
    Regioni508 – 5114G4By similarity
    Regioni544 – 5463G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000076907.
    KOiK02519.
    OMAiNFECGLS.
    OrthoDBiEOG67HJSV.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_B. IF_2_B.
    InterProiIPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0VLU2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDKSIKELA LSVGRPVEKL LEQAREAGLP QRTADDIITT EQQDTLVNYL    50
    KKVHGQESGN TGKIALKRKT TSTAKVASTS GKAKTINVEV RKKQVFAKPN 100
    PEQIAAEAKA RAEAEAKARA EQQAREAAEQ KARLQTEQKA KATLDAMRAA 150
    HQQDSAAQSA PKAAVVVEKR GGGTVKPAPK PAETLEQKKA REAQTAQLKA 200
    TEEAARRKAA EEAQQRTLEQ MRKMASKYSN DDATATIRVI DDSPLASGLV 250
    GQAYEDSFNQ EDREIKRGGA TTNPRAGKKG GRRGQEEQSF VNHNKRGLKS 300
    SQANKHGFEK PVKKQVYDVE IGSSIVVADL AQKMAIKVRE VIKTLMKMGE 350
    LVNQNQTIDQ DTAALVVEEM GHNPVLVSDT QAEDNLLEAA EEARGEQTTR 400
    PPVVTIMGHV DHGKTSLLDR IRRSKVAAGE AGGITQHIGA YHVETDKGII 450
    TFLDTPGHAA FTSMRARGAK ATDIVVLVVA ADDGVMPQTA EAIDHARAAG 500
    TPIIVAINKM DKESADPDRV LNELTTKEIV PEEWGGDVPV AKVSAHTGQG 550
    IDELLDLILI QSELMELKAS AEGAAQGVVI EARVDKGRGA VTSILVQNGT 600
    LNIGDLVLAG SSYGRVRAMS DENGKPIKSA GPSIPVEILG LPEAPMAGDE 650
    VLVVNDEKKA REVADARADR EREKRIERQS AMRLENIMAS MGKKDVPTVN 700
    VVLRTDVRGT LEALNAALHE LSTDEVKVRV ISSGVGAITE SDVILAESSE 750
    AVLLGFNVRA DTAARQKSDQ DGIDIRYYSI IYELIDDVKD AMSGKLAPEH 800
    RETILGVAQV REVFRSSKFG AAAGCMVMEG VIHRNKPIRV LRDDVVIFQG 850
    ELESLRRYKD VVDEVRAGME CGLAVKGYND IKPLDKIEVY DVQIVKRSL 899
    Length:899
    Mass (Da):97,297
    Last modified:April 8, 2008 - v1
    Checksum:i832E70ED099C9BFD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU468230 Genomic DNA. Translation: CAP02458.1.
    RefSeqiYP_001708289.1. NC_010400.1.

    Genome annotation databases

    EnsemblBacteriaiCAP02458; CAP02458; ABSDF3180.
    GeneIDi5987248.
    KEGGiabm:ABSDF3180.
    PATRICi20737053. VBIAciBau88365_3011.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU468230 Genomic DNA. Translation: CAP02458.1 .
    RefSeqi YP_001708289.1. NC_010400.1.

    3D structure databases

    ProteinModelPortali B0VLU2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 509170.ABSDF3180.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAP02458 ; CAP02458 ; ABSDF3180 .
    GeneIDi 5987248.
    KEGGi abm:ABSDF3180.
    PATRICi 20737053. VBIAciBau88365_3011.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000076907.
    KOi K02519.
    OMAi NFECGLS.
    OrthoDBi EOG67HJSV.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_B. IF_2_B.
    InterProi IPR009061. DNA-bd_dom_put.
    IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46955. SSF46955. 1 hit.
    SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SDF.

    Entry informationi

    Entry nameiIF2_ACIBS
    AccessioniPrimary (citable) accession number: B0VLU2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3