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Protein

Translation initiation factor IF-2

Gene

infB

Organism
Acinetobacter baumannii (strain SDF)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi408 – 415GTPUniRule annotation8
Nucleotide bindingi454 – 458GTPUniRule annotation5
Nucleotide bindingi508 – 511GTPUniRule annotation4

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:ABSDF3180
OrganismiAcinetobacter baumannii (strain SDF)
Taxonomic identifieri509170 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
Proteomesi
  • UP000001741 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000937501 – 899Translation initiation factor IF-2Add BLAST899

Structurei

3D structure databases

ProteinModelPortaliB0VLU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini399 – 568tr-type GAdd BLAST170

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni408 – 415G1By similarity8
Regioni433 – 437G2By similarity5
Regioni454 – 457G3By similarity4
Regioni508 – 511G4By similarity4
Regioni544 – 546G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076907.
KOiK02519.
OMAiMSGEVQD.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B. 1 hit.
InterProiIPR009061. DNA-bd_dom_put.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
[Graphical view]
PfamiPF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0VLU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDKSIKELA LSVGRPVEKL LEQAREAGLP QRTADDIITT EQQDTLVNYL
60 70 80 90 100
KKVHGQESGN TGKIALKRKT TSTAKVASTS GKAKTINVEV RKKQVFAKPN
110 120 130 140 150
PEQIAAEAKA RAEAEAKARA EQQAREAAEQ KARLQTEQKA KATLDAMRAA
160 170 180 190 200
HQQDSAAQSA PKAAVVVEKR GGGTVKPAPK PAETLEQKKA REAQTAQLKA
210 220 230 240 250
TEEAARRKAA EEAQQRTLEQ MRKMASKYSN DDATATIRVI DDSPLASGLV
260 270 280 290 300
GQAYEDSFNQ EDREIKRGGA TTNPRAGKKG GRRGQEEQSF VNHNKRGLKS
310 320 330 340 350
SQANKHGFEK PVKKQVYDVE IGSSIVVADL AQKMAIKVRE VIKTLMKMGE
360 370 380 390 400
LVNQNQTIDQ DTAALVVEEM GHNPVLVSDT QAEDNLLEAA EEARGEQTTR
410 420 430 440 450
PPVVTIMGHV DHGKTSLLDR IRRSKVAAGE AGGITQHIGA YHVETDKGII
460 470 480 490 500
TFLDTPGHAA FTSMRARGAK ATDIVVLVVA ADDGVMPQTA EAIDHARAAG
510 520 530 540 550
TPIIVAINKM DKESADPDRV LNELTTKEIV PEEWGGDVPV AKVSAHTGQG
560 570 580 590 600
IDELLDLILI QSELMELKAS AEGAAQGVVI EARVDKGRGA VTSILVQNGT
610 620 630 640 650
LNIGDLVLAG SSYGRVRAMS DENGKPIKSA GPSIPVEILG LPEAPMAGDE
660 670 680 690 700
VLVVNDEKKA REVADARADR EREKRIERQS AMRLENIMAS MGKKDVPTVN
710 720 730 740 750
VVLRTDVRGT LEALNAALHE LSTDEVKVRV ISSGVGAITE SDVILAESSE
760 770 780 790 800
AVLLGFNVRA DTAARQKSDQ DGIDIRYYSI IYELIDDVKD AMSGKLAPEH
810 820 830 840 850
RETILGVAQV REVFRSSKFG AAAGCMVMEG VIHRNKPIRV LRDDVVIFQG
860 870 880 890
ELESLRRYKD VVDEVRAGME CGLAVKGYND IKPLDKIEVY DVQIVKRSL
Length:899
Mass (Da):97,297
Last modified:April 8, 2008 - v1
Checksum:i832E70ED099C9BFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468230 Genomic DNA. Translation: CAP02458.1.

Genome annotation databases

EnsemblBacteriaiCAP02458; CAP02458; ABSDF3180.
KEGGiabm:ABSDF3180.
PATRICi20737053. VBIAciBau88365_3011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468230 Genomic DNA. Translation: CAP02458.1.

3D structure databases

ProteinModelPortaliB0VLU2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP02458; CAP02458; ABSDF3180.
KEGGiabm:ABSDF3180.
PATRICi20737053. VBIAciBau88365_3011.

Phylogenomic databases

HOGENOMiHOG000076907.
KOiK02519.
OMAiMSGEVQD.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B. 1 hit.
InterProiIPR009061. DNA-bd_dom_put.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
[Graphical view]
PfamiPF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIF2_ACIBS
AccessioniPrimary (citable) accession number: B0VLU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.