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B0VLU2

- IF2_ACIBS

UniProt

B0VLU2 - IF2_ACIBS

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Protein

Translation initiation factor IF-2

Gene
infB, ABSDF3180
Organism
Acinetobacter baumannii (strain SDF)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi408 – 4158GTP By similarity
Nucleotide bindingi454 – 4585GTP By similarity
Nucleotide bindingi508 – 5114GTP By similarity

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2
Gene namesi
Name:infB
Ordered Locus Names:ABSDF3180
OrganismiAcinetobacter baumannii (strain SDF)
Taxonomic identifieri509170 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000001741: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 899899Translation initiation factor IF-2UniRule annotationPRO_1000093750Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi509170.ABSDF3180.

Structurei

3D structure databases

ProteinModelPortaliB0VLU2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini399 – 568170tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni408 – 4158G1 By similarity
Regioni433 – 4375G2 By similarity
Regioni454 – 4574G3 By similarity
Regioni508 – 5114G4 By similarity
Regioni544 – 5463G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076907.
KOiK02519.
OMAiNFECGLS.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0VLU2-1 [UniParc]FASTAAdd to Basket

« Hide

MTDKSIKELA LSVGRPVEKL LEQAREAGLP QRTADDIITT EQQDTLVNYL    50
KKVHGQESGN TGKIALKRKT TSTAKVASTS GKAKTINVEV RKKQVFAKPN 100
PEQIAAEAKA RAEAEAKARA EQQAREAAEQ KARLQTEQKA KATLDAMRAA 150
HQQDSAAQSA PKAAVVVEKR GGGTVKPAPK PAETLEQKKA REAQTAQLKA 200
TEEAARRKAA EEAQQRTLEQ MRKMASKYSN DDATATIRVI DDSPLASGLV 250
GQAYEDSFNQ EDREIKRGGA TTNPRAGKKG GRRGQEEQSF VNHNKRGLKS 300
SQANKHGFEK PVKKQVYDVE IGSSIVVADL AQKMAIKVRE VIKTLMKMGE 350
LVNQNQTIDQ DTAALVVEEM GHNPVLVSDT QAEDNLLEAA EEARGEQTTR 400
PPVVTIMGHV DHGKTSLLDR IRRSKVAAGE AGGITQHIGA YHVETDKGII 450
TFLDTPGHAA FTSMRARGAK ATDIVVLVVA ADDGVMPQTA EAIDHARAAG 500
TPIIVAINKM DKESADPDRV LNELTTKEIV PEEWGGDVPV AKVSAHTGQG 550
IDELLDLILI QSELMELKAS AEGAAQGVVI EARVDKGRGA VTSILVQNGT 600
LNIGDLVLAG SSYGRVRAMS DENGKPIKSA GPSIPVEILG LPEAPMAGDE 650
VLVVNDEKKA REVADARADR EREKRIERQS AMRLENIMAS MGKKDVPTVN 700
VVLRTDVRGT LEALNAALHE LSTDEVKVRV ISSGVGAITE SDVILAESSE 750
AVLLGFNVRA DTAARQKSDQ DGIDIRYYSI IYELIDDVKD AMSGKLAPEH 800
RETILGVAQV REVFRSSKFG AAAGCMVMEG VIHRNKPIRV LRDDVVIFQG 850
ELESLRRYKD VVDEVRAGME CGLAVKGYND IKPLDKIEVY DVQIVKRSL 899
Length:899
Mass (Da):97,297
Last modified:April 8, 2008 - v1
Checksum:i832E70ED099C9BFD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU468230 Genomic DNA. Translation: CAP02458.1.
RefSeqiYP_001708289.1. NC_010400.1.

Genome annotation databases

EnsemblBacteriaiCAP02458; CAP02458; ABSDF3180.
GeneIDi5987248.
KEGGiabm:ABSDF3180.
PATRICi20737053. VBIAciBau88365_3011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU468230 Genomic DNA. Translation: CAP02458.1 .
RefSeqi YP_001708289.1. NC_010400.1.

3D structure databases

ProteinModelPortali B0VLU2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 509170.ABSDF3180.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP02458 ; CAP02458 ; ABSDF3180 .
GeneIDi 5987248.
KEGGi abm:ABSDF3180.
PATRICi 20737053. VBIAciBau88365_3011.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076907.
KOi K02519.
OMAi NFECGLS.
OrthoDBi EOG67HJSV.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SDF.

Entry informationi

Entry nameiIF2_ACIBS
AccessioniPrimary (citable) accession number: B0VLU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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