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Protein

Succinyl-CoA ligase [ADP-forming] subunit alpha

Gene

sucD

Organism
Acinetobacter baumannii (strain AYE)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei249 – 2491Tele-phosphohistidine intermediateUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP citrate synthase activity Source: InterPro
  3. cofactor binding Source: InterPro
  4. succinate-CoA ligase (ADP-forming) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciABAU509173:GJXF-785-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinyl-CoA ligase [ADP-forming] subunit alphaUniRule annotation (EC:6.2.1.5UniRule annotation)
Gene namesi
Name:sucDImported
Ordered Locus Names:ABAYE0784Imported
OrganismiAcinetobacter baumannii (strain AYE)Imported
Taxonomic identifieri509173 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000002446 Componenti: Chromosome

Interactioni

Subunit structurei

Heterotetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi509173.ABAYE0784.

Structurei

3D structure databases

ProteinModelPortaliB0VEF3.
SMRiB0VEF3. Positions 2-291.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the succinate/malate CoA ligase alpha subunit family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0074.
HOGENOMiHOG000239685.
KOiK01902.
OMAiITEHIPI.
OrthoDBiEOG644ZT0.

Family and domain databases

Gene3Di3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFiPIRSF001553. SucCS_alpha. 1 hit.
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF52210. SSF52210. 1 hit.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0VEF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLINKDTK VLVQGFTGKN GTFHSAQALD YGTKVVGGVT PGKGGTTHLD
60 70 80 90 100
LPVFNTMKEA VRETNADASV IYVPAPFVLD SIVEAVDSGV GLIVVITEGV
110 120 130 140 150
PTIDMLKAKR YLETNGNGTR LVGPNCPGVI TPGECKIGIM PGHIHQPGRI
160 170 180 190 200
GIISRSGTLT YEAVAQTTKL GLGQSTCIGI GGDPIPGMNQ IEALQLFQDD
210 220 230 240 250
PDTDAIIMIG EIGGTAEEEA AEFIKSNVTK PVVGYIAGVT APKGKRMGHA
260 270 280 290
GAIISGGQGT AEEKFAAFEK AGMAYTRSPA ELGSTMLQVL KEKGLA
Length:296
Mass (Da):30,693
Last modified:April 8, 2008 - v1
Checksum:iC058EDD2BA17CF92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU459141 Genomic DNA. Translation: CAM85740.1.
RefSeqiYP_001712743.1. NC_010410.1.

Genome annotation databases

EnsemblBacteriaiCAM85740; CAM85740; ABAYE0784.
KEGGiaby:ABAYE0784.
PATRICi20725033. VBIAciBau69881_0848.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU459141 Genomic DNA. Translation: CAM85740.1.
RefSeqiYP_001712743.1. NC_010410.1.

3D structure databases

ProteinModelPortaliB0VEF3.
SMRiB0VEF3. Positions 2-291.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi509173.ABAYE0784.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM85740; CAM85740; ABAYE0784.
KEGGiaby:ABAYE0784.
PATRICi20725033. VBIAciBau69881_0848.

Phylogenomic databases

eggNOGiCOG0074.
HOGENOMiHOG000239685.
KOiK01902.
OMAiITEHIPI.
OrthoDBiEOG644ZT0.

Enzyme and pathway databases

BioCyciABAU509173:GJXF-785-MONOMER.

Family and domain databases

Gene3Di3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFiPIRSF001553. SucCS_alpha. 1 hit.
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF52210. SSF52210. 1 hit.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AYEImported.

Entry informationi

Entry nameiB0VEF3_ACIBY
AccessioniPrimary (citable) accession number: B0VEF3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 1, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.