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Reviewed, UniProtKB/Swiss-Prot B0VDK0 (F16PA_ACIBY)

Last modified November 3, 2009. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Fructose-1,6-bisphosphatase class 1
      Short name=FBPase class 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Gene names
Name: fbp
Ordered Locus Names: ABAYE0899
OrganismAcinetobacter baumannii (strain AYE) [Complete proteome] [HAMAP]
Taxonomic identifier509173 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

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Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the FBPase class 1 family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 323323Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
PRO_0000364449

Regions

Region110 – 1134Substrate binding By similarity

Sites

Metal binding881Magnesium 1 By similarity
Metal binding1071Magnesium 1 By similarity
Metal binding1071Magnesium 2 By similarity
Metal binding1091Magnesium 1; via carbonyl oxygen By similarity
Metal binding1101Magnesium 2 By similarity
Metal binding2721Magnesium 2 By similarity
Binding site2001Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
B0VDK0-1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: C3968D65ED820099

FASTA32335,440
        10         20         30         40         50         60 
MSNLTLSQFL QQEKGNLTPE LAQVIDTIAA TCKTIDQALQ KGALAGILGS AGNENVQGET 

        70         80         90        100        110        120 
QKKLDVISND YLIDALKVHP HVGGLASEEL DDFTPAQENG EYLVLFDPLD GSSNIDINMC 

       130        140        150        160        170        180 
VGTIFSILPA KNAITQAQDF MQAGTQQVAA GYVLYGPSTM MALTVGNGVA FFTLDPVTQT 

       190        200        210        220        230        240 
FLLTTENVQV SADTQEFAIN ASNQRHWEQP VKQYIEELLA GKTSVREKDF NMRWVACMVG 

       250        260        270        280        290        300 
DVHRILCRGG IFLYPYDLKD PKKAGRLRLM YEANPMSMLI EQAGGASTTG RVRILEIEPT 

       310        320 
ELHQRVPVII GSKNEVERVT SYH

« Hide

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References

[1]"Comparative analysis of Acinetobacters: three genomes for three lifestyles."
Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S.
PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CU459141 Genomic DNA. Translation: CAM85846.1.
RefSeqYP_001712849.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6000857.
GenomeReviewsGene locus ABAYE0899 in contig CU459141_GR.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQRHWEAP.

Family and domain databases

HAMAPMF_01855.
[Tree]
InterProIPR000146. Fructose_bisphosphatase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PRINTSPR00115. F16BPHPHTASE.
ProDomPD001491. In_FB_phphtase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00124. FBPASE. False negative.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameF16PA_ACIBY
AccessionPrimary (citable) accession number: B0VDK0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: April 8, 2008
Last modified: November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents