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B0VCR1

- B0VCR1_ACIBY

UniProt

B0VCR1 - B0VCR1_ACIBY

Protein
Submitted name:

Isocitrate dehydrogenase

Gene

idh

Organism
Acinetobacter baumannii (strain AYE)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei147 – 1471SubstrateUniRule annotation
    Sitei257 – 2571Critical for catalysis
    Metal bindingi352 – 3521Magnesium or manganeseUniRule annotation
    Sitei422 – 4221Critical for catalysisUniRule annotation
    Binding sitei550 – 5501SubstrateUniRule annotation
    Metal bindingi551 – 5511Magnesium or manganeseUniRule annotation
    Metal bindingi555 – 5551Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciABAU509173:GJXF-975-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
    Gene namesi
    Name:idhImported
    Ordered Locus Names:ABAYE0980Imported
    OrganismiAcinetobacter baumannii (strain AYE)Imported
    Taxonomic identifieri509173 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
    ProteomesiUP000002446: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi509173.ABAYE0980.

    Structurei

    3D structure databases

    ProteinModelPortaliB0VCR1.
    SMRiB0VCR1. Positions 8-741.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni134 – 1418Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiQVQEENH.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B0VCR1-1 [UniParc]FASTAAdd to Basket

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    MAGEKSTIIY TLTDEAPLLA TYSLLPIIET FTKPAGIEIV KSDISVAARV    50
    LAEFADYLSE EQKVSDNLAE LGRLTQDPDT NIIKLPNISA SVAQLTACIK 100
    ELQSKGYAIP DYPENPATEE EKTIKARYGK CLGSAVNPVL REGNSDRRAP 150
    AAVKNYAKKH PHSMSEWKQW SQTHVSHMEE GDFYHGEKSM TLDRPRNVKM 200
    ELITNSGKSI VLKPKVALQE GEIIDSMFMS KKALCDFYEK QLDDCREAGI 250
    LFSLHVKATM MKVSHPIVFG HCVKIYYKEA FEKHGKLFDE LGINVNNGMA 300
    GLYEKIETLP TSLREEIIED LHACQEHRPA LAMVDSAKGI TNFHSPNDII 350
    VDASMPAMIR AGGKMWGADG KQYDAKAVMP ESTFARIYQE MINFCKWHGN 400
    FDPKTMGTVP NVGLMAQKAE EYGSHDKTFE IPEAGIANIT DFDTGEVLLT 450
    QNVEEGDIWR MCQVKDAPIR DWVKLAVTRA RNSGMPAIFW LDPYRPHENE 500
    LIKKVQKYLK DHDTTGLDIQ IMSQVRAMRY TLERVVRGLD TISVTGNILR 550
    DYLTDLFPIM ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVQQLVEEN 600
    HLRWDSLGEF LALAVSLEEM GIKENNARAK LLAKTLDEAT GKLLDNDKSP 650
    SRRTGELDNR GSHFYLSLYW AEALAAQNED AELKAKFAPL AKALAENEQK 700
    IVAELAQVQG KPADIGGYYA VDPAKVSAVM RPSATFNAAL STVQA 745
    Length:745
    Mass (Da):82,674
    Last modified:April 8, 2008 - v1
    Checksum:iC78D1028949F2F92
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU459141 Genomic DNA. Translation: CAM85925.1.
    RefSeqiYP_001712928.1. NC_010410.1.

    Genome annotation databases

    EnsemblBacteriaiCAM85925; CAM85925; ABAYE0980.
    GeneIDi6000900.
    KEGGiaby:ABAYE0980.
    PATRICi20725405. VBIAciBau69881_1029.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU459141 Genomic DNA. Translation: CAM85925.1 .
    RefSeqi YP_001712928.1. NC_010410.1.

    3D structure databases

    ProteinModelPortali B0VCR1.
    SMRi B0VCR1. Positions 8-741.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 509173.ABAYE0980.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAM85925 ; CAM85925 ; ABAYE0980 .
    GeneIDi 6000900.
    KEGGi aby:ABAYE0980.
    PATRICi 20725405. VBIAciBau69881_1029.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi QVQEENH.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci ABAU509173:GJXF-975-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AYEImported.

    Entry informationi

    Entry nameiB0VCR1_ACIBY
    AccessioniPrimary (citable) accession number: B0VCR1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3