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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

idh

Organism
Acinetobacter baumannii (strain AYE)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 1 Mg2+ or Mn2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei147SubstrateUniRule annotation1
Sitei257Critical for catalysisUniRule annotation1
Metal bindingi352Magnesium or manganeseUniRule annotation1
Sitei422Critical for catalysisUniRule annotation1
Binding sitei550SubstrateUniRule annotation1
Metal bindingi551Magnesium or manganeseUniRule annotation1
Metal bindingi555Magnesium or manganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
Name:idhImported
Ordered Locus Names:ABAYE0980Imported
OrganismiAcinetobacter baumannii (strain AYE)Imported
Taxonomic identifieri509173 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
Proteomesi
  • UP000002446 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliB0VCR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni134 – 141Substrate bindingUniRule annotation8

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.
OMAiNSGQMWG.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

B0VCR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGEKSTIIY TLTDEAPLLA TYSLLPIIET FTKPAGIEIV KSDISVAARV
60 70 80 90 100
LAEFADYLSE EQKVSDNLAE LGRLTQDPDT NIIKLPNISA SVAQLTACIK
110 120 130 140 150
ELQSKGYAIP DYPENPATEE EKTIKARYGK CLGSAVNPVL REGNSDRRAP
160 170 180 190 200
AAVKNYAKKH PHSMSEWKQW SQTHVSHMEE GDFYHGEKSM TLDRPRNVKM
210 220 230 240 250
ELITNSGKSI VLKPKVALQE GEIIDSMFMS KKALCDFYEK QLDDCREAGI
260 270 280 290 300
LFSLHVKATM MKVSHPIVFG HCVKIYYKEA FEKHGKLFDE LGINVNNGMA
310 320 330 340 350
GLYEKIETLP TSLREEIIED LHACQEHRPA LAMVDSAKGI TNFHSPNDII
360 370 380 390 400
VDASMPAMIR AGGKMWGADG KQYDAKAVMP ESTFARIYQE MINFCKWHGN
410 420 430 440 450
FDPKTMGTVP NVGLMAQKAE EYGSHDKTFE IPEAGIANIT DFDTGEVLLT
460 470 480 490 500
QNVEEGDIWR MCQVKDAPIR DWVKLAVTRA RNSGMPAIFW LDPYRPHENE
510 520 530 540 550
LIKKVQKYLK DHDTTGLDIQ IMSQVRAMRY TLERVVRGLD TISVTGNILR
560 570 580 590 600
DYLTDLFPIM ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVQQLVEEN
610 620 630 640 650
HLRWDSLGEF LALAVSLEEM GIKENNARAK LLAKTLDEAT GKLLDNDKSP
660 670 680 690 700
SRRTGELDNR GSHFYLSLYW AEALAAQNED AELKAKFAPL AKALAENEQK
710 720 730 740
IVAELAQVQG KPADIGGYYA VDPAKVSAVM RPSATFNAAL STVQA
Length:745
Mass (Da):82,674
Last modified:April 8, 2008 - v1
Checksum:iC78D1028949F2F92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU459141 Genomic DNA. Translation: CAM85925.1.
RefSeqiWP_000896677.1. NC_010410.1.

Genome annotation databases

EnsemblBacteriaiCAM85925; CAM85925; ABAYE0980.
KEGGiaby:ABAYE0980.
PATRICi20725405. VBIAciBau69881_1029.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU459141 Genomic DNA. Translation: CAM85925.1.
RefSeqiWP_000896677.1. NC_010410.1.

3D structure databases

ProteinModelPortaliB0VCR1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM85925; CAM85925; ABAYE0980.
KEGGiaby:ABAYE0980.
PATRICi20725405. VBIAciBau69881_1029.

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.
OMAiNSGQMWG.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB0VCR1_ACIBY
AccessioniPrimary (citable) accession number: B0VCR1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.