Reviewed, UniProtKB/Swiss-Prot B0VBS1 (TRPC_ACIBY)

Names and origin

Protein names

Recommended name:
    Indole-3-glycerol phosphate synthase
      Short name=IGPS
    EC=4.1.1.48

Gene names

Name:	trpC
Ordered Locus Names:	ABAYE1118

Organism

Acinetobacter baumannii (strain AYE) [Complete proteome] [HAMAP]

Taxonomic identifier

509173 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the trpC family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 268	268	Indole-3-glycerol phosphate synthase HAMAP MF_00134		PRO_1000095847

Sequences

	Sequence		Length	Mass (Da)
	B0VBS1-1 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 707CD7187208D29B	FASTA	268	29,911
	10 20 30 40 50 60 MINIQNTILG KIVDRKHEEL AARLKQRNLQ DVEELAKAAT PVRGFANALQ HKRPGVIAEI 70 80 90 100 110 120 KKASPSKGII RADFNPAEIA QQYEQAGAAC LSVLTDVDFF QGADENIAIA RNHCALPALR 130 140 150 160 170 180 KDFLVDPYNV VEARALHADC ILLIVACLSD QQLEEMSKTA FEHQLDVLVE VHDEEELERA 190 200 210 220 230 240 LKLSEQCLLG VNNRNLKTFD VDLNTTIRLK KLLPASRLLI TESGIATPDD VRMMQEHDIH 250 260 SFLVGESFMK QPRPDQAFTA LFGQPQTV

References

[1]

"Comparative analysis of Acinetobacters: three genomes for three lifestyles." Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S. PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CU459141 Genomic DNA. Translation: CAM86046.1.
RefSeq	YP_001713049.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6000989.
GenomeReviews	Gene locus ABAYE1118 in contig CU459141_GR.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PLLCKDF.
Family and domain databases
HAMAP	MF_00134. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GPS_central. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
ProDom	PD001511. IGPS. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPC_ACIBY

Accession

Primary (citable) accession number: B0VBS1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	April 8, 2008
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)