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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Acinetobacter baumannii (strain AYE)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei374Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi170 – 177ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
Ordered Locus Names:ABAYE3718
OrganismiAcinetobacter baumannii (strain AYE)
Taxonomic identifieri509173 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
Proteomesi
  • UP000002446 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, CF(1), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003390131 – 514ATP synthase subunit alphaAdd BLAST514

Proteomic databases

PRIDEiB0VBP5

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0VBP5
SMRiB0VBP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000130111
KOiK02111
OMAiGNAQIKS

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

B0VBP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLNPSEIS ALIKQRIGDL DTSATAKNEG TIVMVSDGIV RIHGLADAMY
60 70 80 90 100
GEMIEFDGGL FGMALNLEQD SVGAVVLGNY LSLQEGQKAR CTGRVLEVPV
110 120 130 140 150
GPELLGRVVD ALGNPIDGKG PIDAKLTDAV EKVAPGVIWR QSVDQPVQTG
160 170 180 190 200
YKSVDTMIPV GRGQRELIIG DRQTGKTAMA IDAIIAQKNS GIKCVYVAIG
210 220 230 240 250
QKQSTIANVV RKLEETGAMA YTTVVAAAAA DPAAMQYLAP YSGCTMGEYF
260 270 280 290 300
RDRGEDALII YDDLSKQAVA YRQISLLLRR PPGREAYPGD VFYLHSRLLE
310 320 330 340 350
RASRVSAEYV EKFTNGAVTG KTGSLTALPI IETQAGDVSA FVPTNVISIT
360 370 380 390 400
DGQIFLETSL FNAGIRPAVN AGISVSRVGG SAQTKIIKKL SGGIRTALAQ
410 420 430 440 450
YRELAAFAQF ASDLDEATRK QLEHGQRVTE LMKQKQYAPY SIADQAVSVY
460 470 480 490 500
ASNEGYMADV EVKKIVDFDA ALIAYFRSEY APLMKQIDET GDYNKDIEAA
510
IKAGIESFKA TQTY
Length:514
Mass (Da):55,397
Last modified:June 10, 2008 - v2
Checksum:i63E4A57970B5A718
GO

Sequence cautioni

The sequence CAM88482 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU459141 Genomic DNA Translation: CAM88482.1 Different initiation.
RefSeqiWP_001186635.1, NC_010410.1

Genome annotation databases

EnsemblBacteriaiCAM88482; CAM88482; ABAYE3718
GeneIDi31349985
KEGGiaby:ABAYE3718

Similar proteinsi

Entry informationi

Entry nameiATPA_ACIBY
AccessioniPrimary (citable) accession number: B0VBP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: March 28, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health