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Reviewed, UniProtKB/Swiss-Prot B0VBC6 (QUEF_ACIBY)

Last modified November 3, 2009. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    NADPH-dependent 7-cyano-7-deazaguanine reductase
    EC=1.7.1.13
Alternative name(s):
    7-cyano-7-carbaguanine reductase
    PreQ(0) reductase
    NADPH-dependent nitrile oxidoreductase
Gene names
Name: queF
Ordered Locus Names: ABAYE1164
OrganismAcinetobacter baumannii (strain AYE) [Complete proteome] [HAMAP]
Taxonomic identifier509173 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter

Protein attributes

Sequence length270 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity.

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00817

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00817

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 270270NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00817
PRO_1000193207

Sequences

Sequence LengthMass (Da)Tools
B0VBC6-1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 68A89510339FB013

FASTA27030,919
        10         20         30         40         50         60 
MSVEQSLLGK ETQYPTSYQP DVLFPIARAQ SREKYAHIQG ITQGKDWWHV FEISWLNAHG 

        70         80         90        100        110        120 
IPQVAIGRIT LPASSPNLIE SKSLKLYFNS LNFTQFDSTQ SFIETVEKDL SAAAGAKVEL 

       130        140        150        160        170        180 
TLFQVDDLEI SKPQGICIDD LMPERLEQHP DATLLKLDES GEEIEVELYS HLLRSNCPVT 

       190        200        210        220        230        240 
GQPDWGTVFI RFKGKKPCYR SLLAYIISYR QHNGFHEQCV EQIFADIWQN LQPEKLMVYA 

       250        260        270 
TYTRRGGLDI NPCRVSDLTW MPKPIRLARQ 

« Hide

References

[1]"Comparative analysis of Acinetobacters: three genomes for three lifestyles."
Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S.
PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CU459141 Genomic DNA. Translation: CAM86091.1.
RefSeqYP_001713094.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6001016.
GenomeReviewsGene locus ABAYE1164 in contig CU459141_GR.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAEHNEFHE.

Family and domain databases

HAMAPMF_00817.
[Tree]
InterProIPR016428. CN_OxRdtase_NADPH-dep_YqcD.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF004750. Nitrile_oxidored_YqcD_prd. 1 hit.
TIGRFAMsTIGR03138. QueF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQUEF_ACIBY
AccessionPrimary (citable) accession number: B0VBC6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: November 3, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents