B0V946 (MQO_ACIBY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	ABAYE2869

Organism

Acinetobacter baumannii (strain AYE) [Complete proteome] [HAMAP]

Taxonomic identifier

509173 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter › Acinetobacter calcoaceticus/baumannii complex

Protein attributes

Sequence length	546 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 546	546	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000099865

Sequences

	Sequence		Length	Mass (Da)
	B0V946 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 8355B36FF5559A4E	FASTA	546	60,451
	10 20 30 40 50 60 MKKFLKYLLV LIILILIAGI VFLFRPIASK QVQTAKDEPV VDAVLVGGGI MSATLGTYFT 70 80 90 100 110 120 ELEPNWQIRM YERLDQVAQE SSNGFNNAGT GHSGFMEMNY TEEKNGKMEI AKAEKVASQF 130 140 150 160 170 180 EVAKQFWSYQ VKQGVLAEPK TFINPVPHIA FVWGDNVKFL EKRYAAMIQS PLFKGMKFTE 190 200 210 220 230 240 DPAVIKQWAP LVMTDRDPTQ KVAATRMEVG SDVNYGSITK QLVNHLNQNP NFKLQTSTEV 250 260 270 280 290 300 TGISQNDDKT WTVSFKNLKT GKTDHVKTRF VFIGAGGAAV KLLQLTGLPE AKQYAGFPVG 310 320 330 340 350 360 GEFLITDNPA ITAQHTAKVY GRAELGAPPM SVPHIDTRYI DGKKYVLFGP FATYSNKFLK 370 380 390 400 410 420 NGSQLDLLAS TNKSNVLPMT TVGLENLDLV KYLVSQVMMS DEDRLNELRK YYPDAKAEDW 430 440 450 460 470 480 RLSQGGQRVQ IIKKEPGKPA TLQFGTEIFA SKDGAVTALL GASPGASTSP YIMLNLLEKA 490 500 510 520 530 540 FPQQTEGKWN QKLHEIVVSY KQDLSKDPVL LDKVRQYTSS TLGLNYTSPF KAANDETAAA PVAKAN

References

[1]

"Comparative analysis of Acinetobacters: three genomes for three lifestyles." Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S. PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AYE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU459141 Genomic DNA. Translation: CAM87696.1.
RefSeq	YP_001714671.1. NC_010410.1.
3D structure databases
ProteinModelPortal	B0V946.
ModBase	Search...
Protein-protein interaction databases
STRING	B0V946.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6003007.
GenomeReviews	Gene locus ABAYE2869 in contig CU459141_GR.
PATRIC	20728907. VBIAciBau69881_2766.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	KKWVPLM.
ProtClustDB	PRK05257.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_ACIBY

Accession

Primary (citable) accession number: B0V946

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program