Skip Header

Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot B0V8P2 (MRAY_ACIBY)

Last modified February 9, 2010. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Phospho-N-acetylmuramoyl-pentapeptide-transferase
    EC=2.7.8.13
Alternative name(s):
    UDP-MurNAc-pentapeptide phosphotransferase
Gene names
Name: mraY
Ordered Locus Names: ABAYE0285
OrganismAcinetobacter baumannii (strain AYE) [Complete proteome] [HAMAP]
Taxonomic identifier509173 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Hide | Top

Protein attributes

Sequence length372 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Function

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity. HAMAP MF_00038

Catalytic activity

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00038

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00038

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_00038.

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily.

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 372372Phospho-N-acetylmuramoyl-pentapeptide-transferase HAMAP MF_00038
PRO_1000090582

Regions

Transmembrane25 – 4521 Potential
Transmembrane73 – 9321 Potential
Transmembrane98 – 11821 Potential
Transmembrane134 – 15421 Potential
Transmembrane176 – 19621 Potential
Transmembrane211 – 23121 Potential
Transmembrane251 – 27121 Potential
Transmembrane275 – 29521 Potential
Transmembrane300 – 32021 Potential
Transmembrane349 – 36921 Potential

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
B0V8P2-1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 3CBE5DE5B81B67F0

FASTA37240,915
        10         20         30         40         50         60 
MLLWLFEQLA GYHSSFQVVR YLTLRSLLSV LTSLTIGLVL GPIMIRKLQA LKYGQAVSSF 

        70         80         90        100        110        120 
APENHAKKMG TPTMGGILIL LSIGISTLLW ADLSNPYVWI VLGVMVVFGA VGWADDWIKI 

       130        140        150        160        170        180 
RYKDNAGLPA RKKFFWTSVA SLGAGIALYL IATQQSNAEY TANMLDLLIP FFKNLSIPLS 

       190        200        210        220        230        240 
IVPLGLAFIV FTYLVINGAS NAVNLTDGLD GLAIMPVVMV ATGLGVFAYL SGDIRFANYL 

       250        260        270        280        290        300 
HIPYVKYTSE LVVICSAMIG AGLAFLWYNA HPAQVFMGDV GALALGAMLG TIAVMVRQEI 

       310        320        330        340        350        360 
VFAIMGGVFV MEAVSVFLQI GSLRMRNKRV FLMAPLHHHY EKQGWKETQV VIRFWIITIM 

       370 
LVVLGLMTLK LR

« Hide

Hide | Top

References

[1]"Comparative analysis of Acinetobacters: three genomes for three lifestyles."
Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E., Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J., Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C., Weissenbach J., Cruveiller S.
PLoS ONE 3:E1805-E1805(2008) [PubMed: 18350144] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Hide | Top

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU459141 Genomic DNA. Translation: CAM85265.1.
RefSeqYP_001712270.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6003537.
GenomeReviewsGene locus ABAYE0285 in contig CU459141_GR.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG708263.
OMAHHHFEQK.

Family and domain databases

HAMAPMF_00038. MraY.
[Tree]
InterProIPR000715. Glycosyl_transferase_4.
IPR018481. Glycosyl_Trfase_4_cons-reg.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view]
PANTHERPTHR22926. Glyco_trans_4. 1 hit.
PTHR22926:SF3. PNAcPpept_trans. 1 hit.
PfamPF00953. Glycos_transf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00445. mraY. 1 hit.
PROSITEPS01347. MRAY_1. 1 hit.
PS01348. MRAY_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameMRAY_ACIBY
AccessionPrimary (citable) accession number: B0V8P2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: February 9, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents