Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

alpha-1,2-Mannosidase

Gene

man1a2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-DRE-964827. Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
Name:man1a2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-070912-390. man1a2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000092968.

Structurei

3D structure databases

SMRiB0V2X9. Positions 160-631.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
GeneTreeiENSGT00390000016529.
HOGENOMiHOG000181988.
HOVERGENiHBG052389.
KOiK01230.
OMAiGAHDEHR.
OrthoDBiEOG7X0VH1.
PhylomeDBiB0V2X9.
TreeFamiTF313420.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.

Sequencei

Sequence statusi: Complete.

B0V2X9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTPALLPLS GRRIPTLSPG ASSFPHHRAT LRLSEKFILL LILSAFITLC
60 70 80 90 100
FGAFFFLPDN SKHKRFDFGL EDVLIPHIET EKESRHGSRQ VIHGVGAHDE
110 120 130 140 150
HRHREEEESL RDKIRADHER ALQEAKEKLR KSKEELKAEI QTAKAKVSED
160 170 180 190 200
LKKKDGPKPL PPVPMPKLVG VNDGDPGDPD TKEKRDKIRE MMKHAWDSYR
210 220 230 240 250
QYGWGHNELK PLAKKGHSTN IFGNSQMGAT IVDALDTLYI MGLHDEFKDG
260 270 280 290 300
QEWIEQNLDF SVNAEVSVFE VNIRFIGGLL AAYYLSGQEV FKLKAVQLAE
310 320 330 340 350
KLLPAFNTPT GIPWAMVNLK SGVGRNWGWA SGGSSILAEF GTLHMEFVHL
360 370 380 390 400
TYLTGNPAYY QKVMHIRKLL AKMDRPNGLY PNYLNPRTGR WGQHHTSVGG
410 420 430 440 450
LGDSFYEYLL KAWLMSDKTD AEARKTYDDA IEAIERHLIR KSNGGLTFIG
460 470 480 490 500
EWKNGHLERK MGHLTCFAGG MFALGADGSP DDKAGHYLQL GAEIAHTCHE
510 520 530 540 550
SYDRTVLKLG PEAFKFDSGL EAVAVRQNEK YYILRPEVIE TYWYMWRFTH
560 570 580 590 600
DPKYRQWGWE AAQAIDKHCR VSGGFSGVKD VYSSNPTYDD VQQSFFLAET
610 620 630 640
LKYLYLLFSS DELLPLENWV FNTEAHPLPV LHLGNITLPG SESQR
Length:645
Mass (Da):73,155
Last modified:April 8, 2008 - v1
Checksum:i7F7ED6450AF6C2E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR391919 Genomic DNA. No translation available.
CT573229 Genomic DNA. No translation available.
RefSeqiNP_001243551.1. NM_001256622.1.
XP_005167594.1. XM_005167537.2.
UniGeneiDr.7784.

Genome annotation databases

EnsembliENSDART00000144248; ENSDARP00000120629; ENSDARG00000041728.
GeneIDi335538.
KEGGidre:335538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR391919 Genomic DNA. No translation available.
CT573229 Genomic DNA. No translation available.
RefSeqiNP_001243551.1. NM_001256622.1.
XP_005167594.1. XM_005167537.2.
UniGeneiDr.7784.

3D structure databases

SMRiB0V2X9. Positions 160-631.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000092968.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000144248; ENSDARP00000120629; ENSDARG00000041728.
GeneIDi335538.
KEGGidre:335538.

Organism-specific databases

CTDi10905.
ZFINiZDB-GENE-070912-390. man1a2.

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
GeneTreeiENSGT00390000016529.
HOGENOMiHOG000181988.
HOVERGENiHBG052389.
KOiK01230.
OMAiGAHDEHR.
OrthoDBiEOG7X0VH1.
PhylomeDBiB0V2X9.
TreeFamiTF313420.

Enzyme and pathway databases

ReactomeiR-DRE-964827. Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2.

Miscellaneous databases

NextBioi20810897.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  2. Ensembl
    Submitted (MAY-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiB0V2X9_DANRE
AccessioniPrimary (citable) accession number: B0V2X9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 11, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.