B0UXP5 (B0UXP5_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Patched 2 EMBL CAQ14877.1

Gene names

Name:	ptc2 EMBL CAQ14877.1 ZFIN ZDB-GENE-980526-196
ORF Names:	CH211-112A3.1-001 EMBL CAQ14877.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAQ14877.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	1354 AA.
Sequence status	Fragment.
Protein existence	Predicted

Ontologies

Gene Ontology (GO)
Biological process	cardioblast differentiation Inferred from genetic interaction. Source: ZFIN negative regulation of smoothened signaling pathway Inferred from mutant phenotype. Source: ZFIN retina development in camera-type eye Inferred from mutant phenotype. Source: ZFIN
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	hedgehog receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAQ14877.1

Sequences

	Sequence		Length	Mass (Da)
	B0UXP5 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 17257223141175A2	FASTA	1,354	150,310
	10 20 30 40 50 60 GGRVNQELKY TRQKIGEEAM FSPQLMIQTP RQEGANILTV EALKQHLDSA IKASRVHVYM 70 80 90 100 110 120 YNRQWTLEHL CYKSGELVTE TNVVDQILEK LHPCLVITPL DCFWEGAKLH SGTFYLPGKP 130 140 150 160 170 180 PLQWTNFDPM GFIAELKMLK YQVDSWEEML VKADVGQGYM NRPCLNPADP DCPLSAPNKN 190 200 210 220 230 240 TTGPFDVAPV LTGGCYGLSK KYMHWQEELI VGGTKKNDSG KLLSAQAFQT MFQLMTPKQM 250 260 270 280 290 300 YEHLKGYDEV SHINWNEDKA AAILEAWQRK YSEAVQQSVP VNSSQKVLTF TTTTLEDILK 310 320 330 340 350 360 SFSDVSVIRI ASGYLLMLAY ACLTMLRWDC AKSQGAVGLA GVLLVTLSVA AGLGLCSLLG 370 380 390 400 410 420 ISFNAATTQV LPFLALGVGV DDVFLLAHAF SETGQNKRIP FEDRTGECLK RTGASVALTS 430 440 450 460 470 480 ISNVTAFFMA ALIPIPALRA FSLQAAVVVV FNFAMVLLIF PAILSMDLYR REDRRFDIFC 490 500 510 520 530 540 CFVSPCANRV IQLEPQAAYA DSSADSSRYS PPPSYSSHSF AQHTQITMQS TVQLRTEYDP 550 560 570 580 590 600 RTQAYYTTAE PHSHISVQPY APNTNPNPNP NRNNNNNNCT NNSSSAVPGV ATDTASCQSP 610 620 630 640 650 660 DGASSTRDLL SQFGDSGIRC LDSPYSRWTF ASFAEKHYAP FLLQSTTKVV VIFLFLALLG 670 680 690 700 710 720 VSLYGTTRVR DGLELTDIVP RETGEYDFIR AQFRYFSFYN MYVVTQRADY AQIQPQLYEL 730 740 750 760 770 780 HQRFGSVKYI LREENGQLPR MWLHYFRDWL LGLQEAFDKD WQAGRITQGN YRNGSDDGVL 790 800 810 820 830 840 AYKLLVQTGR REKTITRQRL VSADGIINPN AFYIYLSAWV SNDPVAYAAS QANIRPHPPE 850 860 870 880 890 900 WLHDRTDSIP ASRLNIPAAE PIEYAQFPFY LNGLRETPQF VEAIESVRAI CNNFSRQGLP 910 920 930 940 950 960 SYPNGYPFLF WEQYVGLRHW LLLSISVVLA CTFLVCAVFL LNPWTAGIIV LVLSLMTVEL 970 980 990 1000 1010 1020 FGMMGLIGIK LSAVPVVILI ASVGIGVEFT VHVALAFLTA IGDRNKRAVL ALEHMFAPVL 1030 1040 1050 1060 1070 1080 DGAFSTLLGV LMLAGSEFDF IVRYFFAVLA ILTVLGVLNG LVLLPVLLSY FGPYPEVSPA 1090 1100 1110 1120 1130 1140 DGQSRLPTPS PEPPPQVVRF TMRPSHTTPG AGSDSSDSEY GSNTTVSGIS QELQQYNLQP 1150 1160 1170 1180 1190 1200 NRGRSARLEE VRIATAGRQG SRQVELPMFP SCSDDSRQQQ IQQHYRSSSH DAAPQPSKRY 1210 1220 1230 1240 1250 1260 CSRDPKRDFG SGHPPPPHRP RMDAFETATE PGGHSGPNHR DRSGAHRPRS HNPYNPHPSH 1270 1280 1290 1300 1310 1320 PSTGPNYCQP ITTVTASASV TVAVHSGVPS QSPAYPSYPS NDSYQTSGDV HNDPHFSDPH 1330 1340 1350 VPFDESHDSS KVEGMELQDL EYDTANVCHT RPSS

References

[1]	Glithero R. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR847548, CR382329 Genomic DNA. Translation: CAQ14798.1. CR382329, CR847548 Genomic DNA. Translation: CAQ14877.1.
IPI	IPI00994727.
UniGene	Dr.116176. Dr.81263.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B0UXP5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
ZFIN	ZDB-GENE-980526-196. ptc2.
Phylogenomic databases
GeneTree	ENSGT00550000074234.
HOGENOM	HBG713504.
HOVERGEN	HBG003801.
OrthoDB	EOG40S0DT.
Gene expression databases
Bgee	B0UXP5.
Family and domain databases
InterPro	IPR003392. Patched. IPR000731. SSD. IPR004766. TM_rcpt_patched. [Graphical view]
Pfam	PF02460. Patched. 1 hit. [Graphical view]
TIGRFAMs	TIGR00918. 2A060602. 1 hit.
PROSITE	PS50156. SSD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0UXP5_DANRE

Accession

Primary (citable) accession number: B0UXP5

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)