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B0UVX7 (GLPB_HISS2) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3
Gene names
Name:glpB
Ordered Locus Names:HSM_1758
OrganismHistophilus somni (strain 2336) (Haemophilus somnus) [Complete proteome] [HAMAP]
Taxonomic identifier228400 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753

Cofactor

FMN By similarity. HAMAP-Rule MF_00753

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753

Subunit structure

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.

Sequence similarities

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
   LigandFlavoprotein
FMN
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycerol catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionsn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753
PRO_1000133364

Sequences

Sequence LengthMass (Da)Tools
B0UVX7 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 8BB79368109BCAB1

FASTA43448,305
        10         20         30         40         50         60 
MAMKFDVVII GGGLAGLTCG IMLQQKGKCC AIINNGQSAM NFSSGSMDLL SQLPNGEKIN 

        70         80         90        100        110        120 
SFEQGYDSLE EQLPNHPYCL FGKQHVLQKA KQFEQLIEKI NLNVTGSYKQ NHFRVTPLGG 

       130        140        150        160        170        180 
LHRTWLSADC IPTMDLHDEH FGYQKITVLG IEGYHDFQPH LLAENLIQHP QFTHCSITTA 

       190        200        210        220        230        240 
LLHLPELDQL RLTSREFRSV NISQLLEHRL AFRELVQEIK QASGDGEAIF LPACFGLDNQ 

       250        260        270        280        290        300 
DFFNKLTLET GLNLYELPTL PPSLVGLRQH KKLKTYFEKL GGFILNGDKA LRAVIEDQQV 

       310        320        330        340        350        360 
KQIYTQLHQE HGIFAEHFVL ASGSFFSNGL VSVFDRLLEP IFDVDMIGNS MIDIQNRLTW 

       370        380        390        400        410        420 
TARRFSSPQP YQSAGVAINS RCQLKKSGQI IKNLYAAGNV IGGYNALELG CGSGVAVVTA 

       430 
LTAADNIIEA QNRV 

« Hide

References

[1]"Complete sequence of Haemophilus somnus 2336."
US DOE Joint Genome Institute
Siddaramappa S., Duncan A.J., Challacombe J.F., Rainey D., Gillaspy A.F., Carson M., Gipson J., Gipson M., Bruce D., Detter J.C., Han C.S., Land M., Tapia R., Thompson L.S., Orvis J., Zaitshik J., Barnes G., Brettin T.S., Dyer D.W., Inzana T.J.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2336.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000947 Genomic DNA. Translation: ACA31538.1.
RefSeqYP_001785078.1. NC_010519.1.

3D structure databases

ProteinModelPortalB0UVX7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING228400.HSM_1758.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA31538; ACA31538; HSM_1758.
GeneID6107675.
KEGGhsm:HSM_1758.
PATRIC20200780. VBIHaeSom93646_1853.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3075.
HOGENOMHOG000278489.
KOK00112.
OMAFRSVNIS.
OrthoDBEOG6K6V62.
ProtClustDBPRK05329.

Enzyme and pathway databases

BioCycHSOM228400:GHWT-1799-MONOMER.
UniPathwayUPA00618; UER00673.

Family and domain databases

HAMAPMF_00753. Glycerol3P_GlpB.
InterProIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsTIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLPB_HISS2
AccessionPrimary (citable) accession number: B0UVX7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways