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Protein

Tol-Pal system protein TolB

Gene

tolB

Organism
Histophilus somni (strain 2336) (Haemophilus somnus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.UniRule annotation

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division

Enzyme and pathway databases

BioCyciHSOM228400:G1GB8-137-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Tol-Pal system protein TolBUniRule annotation
Gene namesi
Name:tolBUniRule annotation
Ordered Locus Names:HSM_0135
OrganismiHistophilus somni (strain 2336) (Haemophilus somnus)
Taxonomic identifieri228400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
Proteomesi
  • UP000008543 Componenti: Chromosome

Subcellular locationi

  • Periplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24UniRule annotationAdd BLAST24
ChainiPRO_500031114025 – 434Tol-Pal system protein TolBUniRule annotationAdd BLAST410

Proteomic databases

PRIDEiB0UVJ6

Interactioni

Subunit structurei

The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0UVJ6
SMRiB0UVJ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TolB family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000004098
KOiK03641
OMAiVREPSWG
OrthoDBiPOG091H04CX

Family and domain databases

Gene3Di2.120.10.30, 1 hit
3.40.50.10070, 1 hit
HAMAPiMF_00671 TolB, 1 hit
InterProiView protein in InterPro
IPR011042 6-blade_b-propeller_TolB-like
IPR011659 PD40
IPR014167 Tol-Pal_TolB
IPR007195 TolB_N
IPR036752 TolB_N_sf
PfamiView protein in Pfam
PF07676 PD40, 4 hits
PF04052 TolB_N, 1 hit
TIGRFAMsiTIGR02800 propeller_TolB, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B0UVJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFSAYLTTL FIVLFSLFIQ TVQAESEVRI VIDEGVDSAR PIAIIPFKWN
60 70 80 90 100
GSDSMPIDVA DIISADLRNS GKFNPIAVSK MPQKPTSASE VISDVWSSLG
110 120 130 140 150
IDAVVVGQVT PNEKGYSIAY QLVDTIGASG NSGEVLSQNQ YAVPKNAIRL
160 170 180 190 200
GAHTISDEVF EKLTAIRGAF RTKIAYVVQK NGGSKPYQVR IADYDGHNQF
210 220 230 240 250
IVYSSSQPLM SPAWSPDGSK LAYVSFENRK SQLIVHDLQS GARRVIAAFP
260 270 280 290 300
GHNGAPAFSP DGSKIAFASS KDGVLNIYVM NLGNGTISQL TSGAGNNTEP
310 320 330 340 350
SWSPDGQSII FTSDRAGGPQ IYQMDVVGNG VSLVSAGRGY SGKISADGSI
360 370 380 390 400
LVMIYGDNIV KKDLATGVTE MLSSTFLDES PSISPNGIMI IYSSTQGLGK
410 420 430
VLQLVSADGR FKARLPSSDG QIKFPAWSPY LNKN
Length:434
Mass (Da):46,356
Last modified:April 8, 2008 - v1
Checksum:iD0E627B336605561
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000947 Genomic DNA Translation: ACA31085.1
RefSeqiWP_012340504.1, NC_010519.1

Genome annotation databases

EnsemblBacteriaiACA31085; ACA31085; HSM_0135
GeneIDi31486410
KEGGihsm:HSM_0135

Similar proteinsi

Entry informationi

Entry nameiTOLB_HISS2
AccessioniPrimary (citable) accession number: B0UVJ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health