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Protein

Transaldolase

Gene

tal

Organism
Histophilus somni (strain 2336) (Haemophilus somnus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei132Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

BioCyciHSOM228400:G1GB8-76-MONOMER.
UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:HSM_0072
OrganismiHistophilus somni (strain 2336) (Haemophilus somnus)
Taxonomic identifieri228400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
Proteomesi
  • UP000008543 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000813951 – 317TransaldolaseAdd BLAST317

Proteomic databases

PRIDEiB0UV30.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliB0UV30.
SMRiB0UV30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000281234.
KOiK00616.
OMAiMAFDKLH.
OrthoDBiPOG091H05RO.

Family and domain databases

CDDicd00957. Transaldolase_TalAB. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00492. Transaldolase_1. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR001585. TAL/FSA.
IPR004730. Transaldolase_1.
IPR018225. Transaldolase_AS.
PANTHERiPTHR10683. PTHR10683. 1 hit.
PTHR10683:SF20. PTHR10683:SF20. 1 hit.
PfamiView protein in Pfam
PF00923. TAL_FSA. 1 hit.
TIGRFAMsiTIGR00874. talAB. 1 hit.
PROSITEiView protein in PROSITE
PS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B0UV30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTQLDALRN MTVVVADTGD IDAIKKYQPQ DATTNPSLIL SASSLPQYAP
60 70 80 90 100
LIDEAIAYAK AKSADKTQQL IDAEDKLAVN IGLEILKIVP GRISTEVDAR
110 120 130 140 150
LSYDTQATVE KARKLIALYN EAGISNDRIL IKIASTWQGI RAAEILEKEG
160 170 180 190 200
INCNLTLLFS KAQARACAEA GVYLISPFVG RILDWYKANS DKKEYAPAED
210 220 230 240 250
PGVISVTKIY NYYKQYGYNT VVMGASFRNV GEITELAGCD RLTIAPALLK
260 270 280 290 300
ELQENSTALV RKLAFKGEVK AKPQPLTESQ FYWQHNSDPM AVEKLADGIR
310
KFAIDQEKLE KMLLEKF
Length:317
Mass (Da):35,103
Last modified:April 8, 2008 - v1
Checksum:i3FB4191A94D3D3BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000947 Genomic DNA. Translation: ACA32385.1.
RefSeqiWP_012341545.1. NC_010519.1.

Genome annotation databases

EnsemblBacteriaiACA32385; ACA32385; HSM_0072.
GeneIDi31486350.
KEGGihsm:HSM_0072.

Similar proteinsi

Entry informationi

Entry nameiTAL_HISS2
AccessioniPrimary (citable) accession number: B0UV30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: February 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome