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B0UUD5

- B0UUD5_HISS2

UniProt

B0UUD5 - B0UUD5_HISS2

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Protein
Alanine racemase
Gene
HSM_1414
Organism
Histophilus somni (strain 2336) (Haemophilus somnus)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei36 – 361Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei132 – 1321Substrate By similarityUniRule annotation
Active sitei255 – 2551Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei303 – 3031Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciHSOM228400:GHWT-1449-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:HSM_1414Imported
OrganismiHistophilus somni (strain 2336) (Haemophilus somnus)Imported
Taxonomic identifieri228400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
ProteomesiUP000008543: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei36 – 361N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi228400.HSM_1414.

Structurei

3D structure databases

ProteinModelPortaliB0UUD5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031446.
KOiK01775.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0UUD5-1 [UniParc]FASTAAdd to Basket

« Hide

MNVIPPTARI SSVALKHNIQ VIKQKAKNSK VIAIVKANAY GHGLEFVSST    50
LHHLVDCFGV ARLSEALRLC TEGITKPILL LEGFFSEDDL PIIAVNNIQT 100
VIHNQEQLYV LKKAKLPNKI KVWLKIDTGM HRLGVDLEQV EDFYQQLVQC 150
SNVKEIGFLS HFSRADELMC GYTEIQLERF LQVTEGKQGE RSIVASSGIL 200
FWQQAYLDWI RPGIIMYGIS PNNTPAEVYG LIPVMTLTSS LITIRNHKKG 250
EPVGYGGSWI SERDTKIGVV AIGYGDGYPR DMPQGTPVYI NGRKVPIVGR 300
VSMDMLTVDL GIESQDKVGD EVILWGKELP IEEISAISGM ISYELITKLT 350
PRVLIEYID 359
Length:359
Mass (Da):40,023
Last modified:April 8, 2008 - v1
Checksum:i6F30F9602F6C7468
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000947 Genomic DNA. Translation: ACA31157.1.
RefSeqiYP_001784734.1. NC_010519.1.

Genome annotation databases

EnsemblBacteriaiACA31157; ACA31157; HSM_1414.
GeneIDi6107294.
KEGGihsm:HSM_1414.
PATRICi20200044. VBIHaeSom93646_1491.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000947 Genomic DNA. Translation: ACA31157.1 .
RefSeqi YP_001784734.1. NC_010519.1.

3D structure databases

ProteinModelPortali B0UUD5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 228400.HSM_1414.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACA31157 ; ACA31157 ; HSM_1414 .
GeneIDi 6107294.
KEGGi hsm:HSM_1414.
PATRICi 20200044. VBIHaeSom93646_1491.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031446.
KOi K01775.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci HSOM228400:GHWT-1449-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2336Imported.

Entry informationi

Entry nameiB0UUD5_HISS2
AccessioniPrimary (citable) accession number: B0UUD5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: July 9, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi