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B0UUD4

- G6PI_HISS2

UniProt

B0UUD4 - G6PI_HISS2

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Histophilus somni (strain 2336) (Haemophilus somnus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei515 – 5151UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciHSOM228400:GHWT-1448-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:HSM_1413
OrganismiHistophilus somni (strain 2336) (Haemophilus somnus)
Taxonomic identifieri228400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
ProteomesiUP000008543: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Glucose-6-phosphate isomerasePRO_1000081240Add
BLAST

Proteomic databases

PRIDEiB0UUD4.

Interactioni

Protein-protein interaction databases

STRINGi228400.HSM_1413.

Structurei

3D structure databases

ProteinModelPortaliB0UUD4.
SMRiB0UUD4. Positions 7-549.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0UUD4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQNINPTQTN AWKALEQHQK DLEQVTIQQL FEQEPTRFND YSLKFAEQIL
60 70 80 90 100
VDYSKNNINQ QTLSLLRQLA KECALNEATE SMFNGEKINR TENRAVLHTA
110 120 130 140 150
LRNCANTPVY VDGKDVMPEV NAVLAKMKSF CQRVISGDWK GYTGKAITDV
160 170 180 190 200
VNIGIGGSDL GPYMVTEALR PYKNHLTMHF VSNVDGTHIA ETLKKVNPET
210 220 230 240 250
TLFLVASKTF TTQETMTNAI SARKWFLAAA QDESQIAKHF AALSTNVKEV
260 270 280 290 300
EKFGIDTHNM FEFWDWVGGR YSLWSAIGLS IALSIGFDNF EQLLAGAHEM
310 320 330 340 350
DKHFRTAPME QNIPITLALI GIWNCNFLGA ETEAMLPYDQ YLHRFAAYFQ
360 370 380 390 400
QGNMESNGKY VDRSGQVINN YQTGPIIWGE PGTNGQHAFY QLIHQGTKII
410 420 430 440 450
PCDFIAPAQT HNVLSDHHNK LLSNFFAQTE ALAFGKTQQE VEAEFIQAGK
460 470 480 490 500
SLDEVKNIVP FKIFTGNKPT NSILVQKITP FTLGALIAMY EHKIFVQGVI
510 520 530 540
FNIYSFDQWG VELGKQLANR ILPELVGDEQ INSHDSSTNG LINQFKSWR
Length:549
Mass (Da):61,893
Last modified:April 8, 2008 - v1
Checksum:i2EA790CC13DC39F4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000947 Genomic DNA. Translation: ACA31156.1.
RefSeqiWP_012340561.1. NC_010519.1.
YP_001784733.1. NC_010519.1.

Genome annotation databases

EnsemblBacteriaiACA31156; ACA31156; HSM_1413.
GeneIDi6107293.
KEGGihsm:HSM_1413.
PATRICi20200042. VBIHaeSom93646_1490.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000947 Genomic DNA. Translation: ACA31156.1 .
RefSeqi WP_012340561.1. NC_010519.1.
YP_001784733.1. NC_010519.1.

3D structure databases

ProteinModelPortali B0UUD4.
SMRi B0UUD4. Positions 7-549.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 228400.HSM_1413.

Proteomic databases

PRIDEi B0UUD4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACA31156 ; ACA31156 ; HSM_1413 .
GeneIDi 6107293.
KEGGi hsm:HSM_1413.
PATRICi 20200042. VBIHaeSom93646_1490.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261371.
KOi K01810.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci HSOM228400:GHWT-1448-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2336.

Entry informationi

Entry nameiG6PI_HISS2
AccessioniPrimary (citable) accession number: B0UUD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3