SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B0UT19

- XYLA_HISS2

UniProt

B0UT19 - XYLA_HISS2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Xylose isomerase

Gene
xylA, HSM_0936
Organism
Histophilus somni (strain 2336) (Haemophilus somnus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011 By similarity
Active sitei104 – 1041 By similarity
Metal bindingi232 – 2321Magnesium 1 By similarity
Metal bindingi268 – 2681Magnesium 1 By similarity
Metal bindingi268 – 2681Magnesium 2 By similarity
Metal bindingi271 – 2711Magnesium 2 By similarity
Metal bindingi296 – 2961Magnesium 1 By similarity
Metal bindingi307 – 3071Magnesium 2 By similarity
Metal bindingi309 – 3091Magnesium 2 By similarity
Metal bindingi339 – 3391Magnesium 1 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Pentose shunt, Xylose metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciHSOM228400:GHWT-968-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomerase (EC:5.3.1.5)
Gene namesi
Name:xylA
Ordered Locus Names:HSM_0936
OrganismiHistophilus somni (strain 2336) (Haemophilus somnus)
Taxonomic identifieri228400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
ProteomesiUP000008543: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 439439Xylose isomeraseUniRule annotationPRO_1000081030Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi228400.HSM_0936.

Structurei

3D structure databases

ProteinModelPortaliB0UT19.
SMRiB0UT19. Positions 2-439.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000252293.
KOiK01805.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0UT19-1 [UniParc]FASTAAdd to Basket

« Hide

MSNYFDKIAK VNYEGANSTN PFAFKHYNPN EVILGKTVEE HLRLAVCYWH    50
TFCWTGNDMF GAGSLDRSWQ KTGDLLVGAK QKAEIAFEFF QKLGVPYYSF 100
HDVDIAPESN NFKEYLHNFN TIVDILEKKQ SETGVKLLWG TANCFTNPRY 150
MSGASTNPNP EVFAWAAAQV FTAMNATQRL GGENYVLWGG REGYETLLNT 200
DLKREREQIG RFMQLVVEHK YKIGFQGTLL IEPKPQEPTK HQYDYDVATV 250
YGFLKQFGLE NEIKVNIEAN HATLAGHTFQ HEIATATSLG IFGSIDANRG 300
DPQLGWDTDQ FPNSVEENTL AMYEILKAGG FTTGGFNFDA KIRRQSTDPY 350
DLFHAHIGAM DVLALSLKRA AKMIEDQTLQ KVVDNRYAGW DQELGQKILS 400
GKASLEDLAK IVETQGLDPK PVSGQQEYLE NLVNSYLYR 439
Length:439
Mass (Da):49,604
Last modified:April 8, 2008 - v1
Checksum:i00A850D6B2BF816D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000947 Genomic DNA. Translation: ACA32619.1.
RefSeqiWP_012341741.1. NC_010519.1.
YP_001784268.1. NC_010519.1.

Genome annotation databases

EnsemblBacteriaiACA32619; ACA32619; HSM_0936.
GeneIDi6108768.
KEGGihsm:HSM_0936.
PATRICi20199047. VBIHaeSom93646_1001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000947 Genomic DNA. Translation: ACA32619.1 .
RefSeqi WP_012341741.1. NC_010519.1.
YP_001784268.1. NC_010519.1.

3D structure databases

ProteinModelPortali B0UT19.
SMRi B0UT19. Positions 2-439.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 228400.HSM_0936.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACA32619 ; ACA32619 ; HSM_0936 .
GeneIDi 6108768.
KEGGi hsm:HSM_0936.
PATRICi 20199047. VBIHaeSom93646_1001.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000252293.
KOi K01805.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci HSOM228400:GHWT-968-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2336.

Entry informationi

Entry nameiXYLA_HISS2
AccessioniPrimary (citable) accession number: B0UT19
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: September 3, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi