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Protein

Xylose isomerase

Gene

xylA

Organism
Histophilus somni (strain 2336) (Haemophilus somnus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciHSOM228400:G1GB8-984-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:HSM_0936
OrganismiHistophilus somni (strain 2336) (Haemophilus somnus)
Taxonomic identifieri228400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHistophilus
Proteomesi
  • UP000008543 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000810301 – 439Xylose isomeraseAdd BLAST439

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0UT19
SMRiB0UT19
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

B0UT19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNYFDKIAK VNYEGANSTN PFAFKHYNPN EVILGKTVEE HLRLAVCYWH
60 70 80 90 100
TFCWTGNDMF GAGSLDRSWQ KTGDLLVGAK QKAEIAFEFF QKLGVPYYSF
110 120 130 140 150
HDVDIAPESN NFKEYLHNFN TIVDILEKKQ SETGVKLLWG TANCFTNPRY
160 170 180 190 200
MSGASTNPNP EVFAWAAAQV FTAMNATQRL GGENYVLWGG REGYETLLNT
210 220 230 240 250
DLKREREQIG RFMQLVVEHK YKIGFQGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE NEIKVNIEAN HATLAGHTFQ HEIATATSLG IFGSIDANRG
310 320 330 340 350
DPQLGWDTDQ FPNSVEENTL AMYEILKAGG FTTGGFNFDA KIRRQSTDPY
360 370 380 390 400
DLFHAHIGAM DVLALSLKRA AKMIEDQTLQ KVVDNRYAGW DQELGQKILS
410 420 430
GKASLEDLAK IVETQGLDPK PVSGQQEYLE NLVNSYLYR
Length:439
Mass (Da):49,604
Last modified:April 8, 2008 - v1
Checksum:i00A850D6B2BF816D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000947 Genomic DNA Translation: ACA32619.1
RefSeqiWP_012341741.1, NC_010519.1

Genome annotation databases

EnsemblBacteriaiACA32619; ACA32619; HSM_0936
GeneIDi31487235
KEGGihsm:HSM_0936

Similar proteinsi

Entry informationi

Entry nameiXYLA_HISS2
AccessioniPrimary (citable) accession number: B0UT19
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: April 25, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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