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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Methylobacterium sp. (strain 4-46)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMSP426117:GI2I-6346-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:M446_6270
OrganismiMethylobacterium sp. (strain 4-46)
Taxonomic identifieri426117 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000001185 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 639639Chaperone protein DnaKPRO_1000119731Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei198 – 1981Phosphothreonine; by autocatalysisUniRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiB0UR84.

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi426117.M446_6270.

Structurei

3D structure databases

ProteinModelPortaliB0UR84.
SMRiB0UR84. Positions 1-595.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0UR84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKVIGIDLG TTNSCVAVME GTQPKVIENA EGARTTPSIV AFTDEGERLV
60 70 80 90 100
GQPAKRQAVT NPSRTFFAIK RLIGRTYDDP MTQKDKGLVP YHIVRAGNGD
110 120 130 140 150
AWVEADGKQF SPSQISAFTL QKMKETAESY LGQPVTQAVI TVPAYFNDAQ
160 170 180 190 200
RQATKDAGKI AGLEVLRIIN EPTAAALAYG LDKKKSGVIA VYDLGGGTFD
210 220 230 240 250
VSILEIGDGV FEVKSTNGDT FLGGEDFDNR IVEYLAAEFK REQGIDLTRD
260 270 280 290 300
KLALQRLKEA AEKAKIELSS ATQTEINLPY ITADASGPKH LALKLSRAKF
310 320 330 340 350
ESLVDDLIQR TIEPCRKALK DAGVAASEID EVVLVGGMTR MPKIQDVVKT
360 370 380 390 400
FFGKEPHKGV NPDEVVAIGA AVQAGVLQGD VKDVLLLDVT PLSLGIETLG
410 420 430 440 450
GVFTRLIDRN TTIPTKKSQV FSTAEDNQNA VTIRVFQGER EMAADNKLLG
460 470 480 490 500
QFDLVGIPPA PRGVPQIEVT FDIDANGIVN VTAKDKATGK EHQIRIQASG
510 520 530 540 550
GLSDTEIQRM VQEAEANAAE DKKRRELVEV KNQGESLVHA TEKSVKEYGD
560 570 580 590 600
KVSESDRAGI STAIDALRQA LAGEDVETIK ARTTDLMQAS MKLGEAMYAA
610 620 630
QAGGGEAASA GAEDPQAKKD DVIDADFQEV DDKDHKKRA
Length:639
Mass (Da):68,742
Last modified:April 8, 2008 - v1
Checksum:iEECBBCB2B76A9819
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000943 Genomic DNA. Translation: ACA20536.1.
RefSeqiWP_012335914.1. NC_010511.1.

Genome annotation databases

EnsemblBacteriaiACA20536; ACA20536; M446_6270.
KEGGimet:M446_6270.
PATRICi22593829. VBIMetSp32184_6214.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000943 Genomic DNA. Translation: ACA20536.1.
RefSeqiWP_012335914.1. NC_010511.1.

3D structure databases

ProteinModelPortaliB0UR84.
SMRiB0UR84. Positions 1-595.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi426117.M446_6270.

Proteomic databases

PRIDEiB0UR84.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA20536; ACA20536; M446_6270.
KEGGimet:M446_6270.
PATRICi22593829. VBIMetSp32184_6214.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiEKMAPPQ.
OrthoDBiPOG091H01UE.

Enzyme and pathway databases

BioCyciMSP426117:GI2I-6346-MONOMER.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_METS4
AccessioniPrimary (citable) accession number: B0UR84
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.