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B0UQS5 (GLSA_METS4) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:M446_4570
OrganismMethylobacterium sp. (strain 4-46) [Complete proteome] [HAMAP]
Taxonomic identifier426117 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Glutaminase HAMAP-Rule MF_00313
PRO_1000119534

Sites

Binding site641Substrate By similarity
Binding site1141Substrate By similarity
Binding site1601Substrate By similarity
Binding site1671Substrate By similarity
Binding site1911Substrate By similarity
Binding site2431Substrate By similarity
Binding site2611Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
B0UQS5 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 6D75F9B0517EFFAB

FASTA30933,331
        10         20         30         40         50         60 
MTDLTRVVTE IAEEMRARPD RGEVATYIPE LARMDPRAFG MVVIDADGEV AAAGDCDVPF 

        70         80         90        100        110        120 
SIQSISKVFT LTLALGMVGD RLWRRVGREP SGSPFNSIVQ LEYERGIPRN PFINAGAIAV 

       130        140        150        160        170        180 
TDVILSRHQP REALGEILRF LQFLAGDAAI AIDESVAASE QRTGYRNMAL ANFMKAHGVL 

       190        200        210        220        230        240 
DNPVPYLLGV YFHHCAIAMT CRQLAEAGRF LAHSGRHPAT GHLVVQPERA RRINAVMLTC 

       250        260        270        280        290        300 
GHYDGSGEFA YRVGLPGKSG VGGGILAIAP GRASIAVWSP GLDAAGNSHL GRIALEMLTK 


RLGWSIFGQ 

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium sp. 4-46."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Ivanova N., Marx C.J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 4-46.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000943 Genomic DNA. Translation: ACA18911.1.
RefSeqYP_001771345.1. NC_010511.1.

3D structure databases

ProteinModelPortalB0UQS5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING426117.M446_4570.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA18911; ACA18911; M446_4570.
GeneID6130140.
KEGGmet:M446_4570.
PATRIC22590314. VBIMetSp32184_4487.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycMSP426117:GI2I-4615-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_METS4
AccessionPrimary (citable) accession number: B0UQS5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families