B0UP01 (B0UP01_METS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-0-acyl N-acetylglucosamine deacetylase EMBL ACA17609.1

Gene names

Ordered Locus Names:

M446_3203

Organism

Methylobacterium sp. (strain 4-46) [Complete proteome] [HAMAP]

Taxonomic identifier

426117 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	436 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0UP01 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 5AEE604EB10FE9ED	FASTA	436	46,747
	10 20 30 40 50 60 MREGRGKDWC GHGRAASGED QATLAAPFEV VGPGLHTGRT CRVIVEPAPP DFGIRFRTLR 70 80 90 100 110 120 QAADFTPATW RVRVPSRMST ALDLGAGGRL RTVEHLMASL ASCGIDNAAV TVAGGEIPIL 130 140 150 160 170 180 DGSAGPWCGL IGRAGLRRQA AARHAIALLA PFEVSDAHGF VRGEPCDRCC VDVSTDRMPG 190 200 210 220 230 240 FGVLRWSGAI DPETFRSAIA PSRSFGNASV LWRAALRSRL ATRLLPPDLR HRLWLRSFHS 250 260 270 280 290 300 QTVTGCTGPT PAEPRPECQH PISPWTLSRM IVTAPEPLLR GARPGRVAVV LGGRILGGAR 310 320 330 340 350 360 FPDEPVRHRV LDLLGDLALA GRPLRARIVA NCPTHALTFA FVAELMARPE LWRLEPAPAA 370 380 390 400 410 420 PARARPERGP GIPPGKAPRR SPPARQDRMF TARAATSATV RSEIDASAII RSLARCVSGS 430 VSVGEKAVAL VKERNR

References

[1]

"Complete sequence of chromosome of Methylobacterium sp. 4-46." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 4-46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000943 Genomic DNA. Translation: ACA17609.1.
RefSeq	YP_001770043.1. NC_010511.1.
3D structure databases
ProteinModelPortal	B0UP01.
ModBase	Search...
Protein-protein interaction databases
STRING	B0UP01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6134027.
GenomeReviews	Gene locus M446_3203 in contig CP000943_GR.
KEGG	met:M446_3203.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG482342.
OMA	IAFRRVA.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 2 hits. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

B0UP01_METS4

Accession

Primary (citable) accession number: B0UP01

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	November 16, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)