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B0UJS6 (B0UJS6_METS4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:M446_2579
OrganismMethylobacterium sp. (strain 4-46) [Complete proteome] [HAMAP]
Taxonomic identifier426117 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2291Iron By similarity HAMAP MF_00323
Metal binding3101Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B0UJS6 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: E89AE886DEBE1FB4

FASTA36040,543
        10         20         30         40         50         60 
MNEVTKPAVL ERGATPVSPV APGALPAEHA RVAWGRVGVL LMNLGTPEAT SYWPMRRYLK 

        70         80         90        100        110        120 
EFLSDRRVIE VPRAIWWPLL NLVILTKRPG PKGRDYASIW NNDLDEGPLK TITRGQAEKL 

       130        140        150        160        170        180 
QAAMGGRVVV DWAMRYGKPE VEGRIQALLD QGCDRILLVP LYPQYAAATS ATACDQAFRA 

       190        200        210        220        230        240 
LMKMRWQPTV RVSPPYHDDP VYIDAVASAI RRDLEKLDFE PEVILTSFHG VPKSYLLKGD 

       250        260        270        280        290        300 
PYHCQCVKTG RLIREALGYA PERMRVTFQS RFGNEEWLKP YTDETVKELA ASGVKRLAIV 

       310        320        330        340        350        360 
APGFTADCLE TLEELDGENR HYFEEGGGTH FAYLPCLNDG PEGMRVIEHV VQRELRGWID

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References

[1]"Complete sequence of chromosome of Methylobacterium sp. 4-46."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Ivanova N., Marx C.J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 4-46.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000943 Genomic DNA. Translation: ACA17018.1.
RefSeqYP_001769452.1. NC_010511.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB0UJS6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6131685.
GenomeReviewsGene locus M446_2579 in contig CP000943_GR.
KEGGmet:M446_2579.
PATRIC22586416. VBIMetSp32184_2560.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMAIRPAKSA.
ProtClustDBCLSK979865.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0UJS6_METS4
AccessionPrimary (citable) accession number: B0UJS6
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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