B0UIR9 (B0UIR9_METS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA topoisomerase IV, B subunit EMBL ACA18695.1
EC=5.99.1.3 EMBL ACA18695.1

Gene names

Ordered Locus Names:

M446_4352

Organism

Methylobacterium sp. (strain 4-46) [Complete proteome] [HAMAP]

Taxonomic identifier

426117 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	682 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the type II topoisomerase family. RuleBase RU000380

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000380 SAAS SAAS002288 Nucleotide-binding
Molecular function	Isomerase Topoisomerase RuleBase RU000380 SAAS SAAS002288
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0UIR9 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 61BC43408C73B658	FASTA	682	74,502
	10 20 30 40 50 60 MSDPARDLFA PGAKPAPGDP ESGAKRPRPV AVPSPAAEAG YDASAIEVLE GLEPVRRRPG 70 80 90 100 110 120 MYIGGTDEKA LHHLFAEVID NSMDEAVAGH ATFIEVELEE GGILSVTDNG RGIPVDPHPK 130 140 150 160 170 180 FPGRSALEVI MTTLHAGGKF DSKVYETSGG LHGVGVSVVN ALSDRLEVEV ARNQTLYRQH 190 200 210 220 230 240 FSRGVPQGGL EQVGRVQNRR GTKVRFHPDP QIFGALAFDP RRLFKMARSK AYLFGGVEIR 250 260 270 280 290 300 WRCAPALVEG IEGVPAEAVH RFPAGLRDYL AQEIDGKELV TDALFTGKVT RPGSHGSLEW 310 320 330 340 350 360 AVAWLTHDDG FSSSYCNTVP TPEGGTHESG LRIALLRALR DHAERVGQVK RVQAVTTDDV 370 380 390 400 410 420 MATCASMLSV FIREPEFQGQ TKDKLATLEA SRIVEAAVRD AFDHWLAASP TQANKLLDWV 430 440 450 460 470 480 IDRAEERLRR RQEKEVARKT ATRKLRLPGK LADCSKAGAA GSEIFIVEGD SAGGSAKQAR 490 500 510 520 530 540 DRASQAVLPL RGKILNVASA SRDKLGANQL LSDLTQALGC GTGSHYRDDD LRYEKVIIMT 550 560 570 580 590 600 DADVDGAHIA SLLITFFYRQ MPKLIEKGHL YLAVPPLYRL SQGAKTAYAR DDRHKEQLIK 610 620 630 640 650 660 TVFKNGKVEI GRFKGLGEMM PGQLKETTMD PSKRTLLRVE VLDEAREATG DAVERLMGNK 670 680 PEARFAFISE RAVFADEAEL DI

References

[1]

"Complete sequence of chromosome of Methylobacterium sp. 4-46." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 4-46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000943 Genomic DNA. Translation: ACA18695.1.
RefSeq	YP_001771129.1. NC_010511.1.
3D structure databases
ProteinModelPortal	B0UIR9.
ModBase	Search...
Protein-protein interaction databases
STRING	B0UIR9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6134699.
GenomeReviews	Gene locus M446_4352 in contig CP000943_GR.
KEGG	met:M446_4352.
PATRIC	22589852. VBIMetSp32184_4259.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	QARDKEF.
ProtClustDB	PRK05559.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR005737. TopoIV_B_Gneg. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 1 hit.
KO	K02622.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01055. ParE_Gneg. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0UIR9_METS4

Accession

Primary (citable) accession number: B0UIR9

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)