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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methylobacterium sp. (strain 4-46)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:M446_2480
OrganismiMethylobacterium sp. (strain 4-46)
Taxonomic identifieri426117 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000001185 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001989231 – 586Arginine--tRNA ligaseAdd BLAST586

Proteomic databases

PRIDEiB0UI81

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi426117.M446_2480

Structurei

3D structure databases

ProteinModelPortaliB0UI81
SMRiB0UI81
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi130 – 140"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 2 hits
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B0UI81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIFAAFEER IGEALATLTR AGQLPEGLDL GRVVVEPPRD PGHGDLATNA
60 70 80 90 100
ALVLAKEART NPKALAELLA AELRQDPRVT EASVAGPGFL NLRLAPEVFA
110 120 130 140 150
EVVRAALASG EAFGRGARRP GLVNVEYVSA NPTGPMHVGH GRGAVFGDAL
160 170 180 190 200
ANLLAASGRE VVREYYINDA GAQVDVLARS AYLRYREALG DAIGAIPEGL
210 220 230 240 250
YPGDYLKPVG RRLAETHGRA LLREPESAWL PVVRDFAIAA MMDLIRDDLA
260 270 280 290 300
ALGIRHDVFF SERTLQGGGD GGAVGALIAE LREKGLVYVG RLPPPKGQLP
310 320 330 340 350
EDWEDRDQTL FRSTAFGDDI DRPLLKSDGT YTYFASDIAY HASKVARGAT
360 370 380 390 400
DLIDVLGADH GGYVKRMQAA VRAVSDGRAS LDVKLCQLVR LLRGGEPVKM
410 420 430 440 450
SKRAGEFVTL REVIDEVGRD PVRFMMLYRK NDATLDFDLA KVVEQSKDNP
460 470 480 490 500
VFYVQYAHAR TASVFRQARE AFPGEDLSPQ ALAGADLSLL RDSGEADIMR
510 520 530 540 550
LVAQYPRVIE AAGSAHEPHR LAFYLYELAS AFHSFWNKGK DLPQLRFVNQ
560 570 580
TDRKSTLSRL ALVAALRGVL ASGLGILGVT APDEMR
Length:586
Mass (Da):63,543
Last modified:April 8, 2008 - v1
Checksum:i641F3C68F63D7130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000943 Genomic DNA Translation: ACA16932.1
RefSeqiWP_012332339.1, NC_010511.1

Genome annotation databases

EnsemblBacteriaiACA16932; ACA16932; M446_2480
KEGGimet:M446_2480

Similar proteinsi

Entry informationi

Entry nameiSYR_METS4
AccessioniPrimary (citable) accession number: B0UI81
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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