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B0UAB0 (B0UAB0_METS4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186
Ordered Locus Names:M446_1966
OrganismMethylobacterium sp. (strain 4-46) [Complete proteome] [HAMAP]
Taxonomic identifier426117 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length507 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding417 – 4215ATP By similarity HAMAP MF_00186

Sites

Binding site171Substrate By similarity HAMAP MF_00186
Binding site211ATP By similarity HAMAP MF_00186
Binding site871Substrate By similarity HAMAP MF_00186
Binding site1391Substrate By similarity HAMAP MF_00186
Binding site2481Substrate By similarity HAMAP MF_00186
Binding site2701ATP By similarity HAMAP MF_00186
Binding site3131ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
B0UAB0 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 5E0FA4FE8479111F

FASTA50754,252
        10         20         30         40         50         60 
MASPPHSPLI LAIDQGTTST RALLFRADTS VAALAQAEFP QHFPASGWVE HEPDDLWRTT 

        70         80         90        100        110        120 
LATCRAALER AGARAGDVAA IGITNQRETT LVWDRRTGEA VHRAIVWQDR RTAGLCARLR 

       130        140        150        160        170        180 
AQGHEPLVAA RTGLILDPYF SGTKIAWILD NVPGARARAE AGDLAFGTVD SYLLWRLTGG 

       190        200        210        220        230        240 
RLHVTDATNA ARTLLFDIHR GTWDDDLLGL LGIPRAMLPE VRDSSGDFGA TDPDLFGAAI 

       250        260        270        280        290        300 
PIRGVAGDQQ AATVGQACFR PGMVKSTYGT GCFALLNTGA QPVASGNKLL TTIAYQLDGR 

       310        320        330        340        350        360 
RTYALEGSIF VAGAAVQWLR DGLKVVGSAA ETGDLAERAD PAQDVYLVPA FVGLGAPYWE 

       370        380        390        400        410        420 
PDVRGALYGL TRNTGPAELA RAALESVCYQ TADLLAAMRA DWPDGDGRAT VLRVDGGMVA 

       430        440        450        460        470        480 
SDWTMQRLAD LLAAPVDRPE VKETTALGAA YLAGLACGLY PDPEHFADHW RLERRFAPAM 

       490        500 
DAPVRARKLA GWRKAVGCLL GRTEPVP

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References

[1]"Complete sequence of chromosome of Methylobacterium sp. 4-46."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Ivanova N., Marx C.J., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 4-46.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000943 Genomic DNA. Translation: ACA16431.1.
RefSeqYP_001768865.1. NC_010511.1.

3D structure databases

ProteinModelPortalB0UAB0.
SMRB0UAB0. Positions 9-500.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0UAB0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6130952.
GenomeReviewsGene locus M446_1966 in contig CP000943_GR.
KEGGmet:M446_1966.
PATRIC22585136. VBIMetSp32184_1930.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG511469.
OMACYQTRDL.
ProtClustDBCLSK2478134.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0UAB0_METS4
AccessionPrimary (citable) accession number: B0UAB0
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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