B0U8Q8 (B0U8Q8_METS4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase EMBL ACA17828.1
EC=2.3.1.37 EMBL ACA17828.1

Gene names

Ordered Locus Names:

M446_3442

Organism

Methylobacterium sp. (strain 4-46) [Complete proteome] [HAMAP]

Taxonomic identifier

426117 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Acyltransferase EMBL ACA17828.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0U8Q8 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 095F028866E0E24D	FASTA	433	46,075
	10 20 30 40 50 60 MPYASVHATS ARPASPPRAG SGPDYQAIFR SAVDRLHDER RYRVFADIER VAGRFPVARR 70 80 90 100 110 120 RLPDGSCRDI TVWCSNDYLG MGQHPDVVQA LTRTAARCGV GAGGTRNIAG TSSPLVDLER 130 140 150 160 170 180 ELADLHGKEA ALVFTSGYVS NQTGIATLAR LIPDCLILSD AYNHNSMIEG VRQSGCDKRV 190 200 210 220 230 240 FRHNDLAHLE ALLAEAGARP KLIAFESVYS MDGDVAPIAA ICDLAARYGA MTYIDEVHAV 250 260 270 280 290 300 GLYGPRGAGI AERDGVMHRL DVIEGTLAKG FGVVGGYIAG SAVLCDAVRS HAPGFIFTTA 310 320 330 340 350 360 LPPAIAAAAT ASIRHLKRSG AERAAHQRQA ARTKAALAGA GLPVLATPTH IVPVMVGDAE 370 380 390 400 410 420 RCRAAADRLL ERHGIYIQPI NYPTVPRGTE RLRITPSPFH DEADIARLTA ALVEVWDALG 430 LPRAGTAFAE AAE

References

[1]

"Complete sequence of chromosome of Methylobacterium sp. 4-46." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 4-46.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000943 Genomic DNA. Translation: ACA17828.1.
RefSeq	YP_001770262.1. NC_010511.1.
3D structure databases
ProteinModelPortal	B0U8Q8.
SMR	B0U8Q8. Positions 24-416.
ModBase	Search...
Protein-protein interaction databases
STRING	B0U8Q8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6131877.
GenomeReviews	Gene locus M446_3442 in contig CP000943_GR.
KEGG	met:M446_3442.
PATRIC	22588091. VBIMetSp32184_3393.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG649839.
OMA	MARIDIL.
ProtClustDB	PRK09064.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0U8Q8_METS4

Accession

Primary (citable) accession number: B0U8Q8

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)