Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B0U741

- GCH4_XYLFM

UniProt

B0U741 - GCH4_XYLFM

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Xylella fastidiosa (strain M12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 2 (05 May 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei155 – 1551May be catalytically importantUniRule annotation

    GO - Molecular functioni

    1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciXFAS405440:GH0D-957-MONOMER.
    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
    Gene namesi
    Name:folE2UniRule annotation
    Ordered Locus Names:Xfasm12_0929
    OrganismiXylella fastidiosa (strain M12)
    Taxonomic identifieri405440 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
    ProteomesiUP000008539: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 298298GTP cyclohydrolase FolE2PRO_0000372038Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi405440.Xfasm12_0929.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase IV family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1469.
    HOGENOMiHOG000247517.
    KOiK09007.
    OMAiAGRTTIQ.
    OrthoDBiEOG6X6RBH.

    Family and domain databases

    HAMAPiMF_01527_B. GTP_cyclohydrol_B.
    InterProiIPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view]
    PfamiPF02649. GCHY-1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0U741-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTSIPDVAV HDSPAIAAPL RWVGMDGIVV PVQLTIADGG QHVIGRARAQ    50
    IDLPAMEVKG IHMSRLYRLL DTHAVEPLTP VGICGLLSAM VNSHADCAST 100
    AARVDWYFDW LRRVPALVSN DLSGWRGYPV WLRAEYSAGH VQFWLCVEVG 150
    YSSTCPCSAA LARQMLADAF LQEHVEVSAL SPETVADWLR SNGSYATPHS 200
    QRSLARIEVA LTEQAVELGL PALVDCAERI LSTPVQAAVR RVDEQAFARL 250
    NGANLMYVED ATRRLQHGLA IHYSAFRVHV RHLESLHPHD AVASTADE 298
    Length:298
    Mass (Da):32,583
    Last modified:May 5, 2009 - v2
    Checksum:i2104418A31A1C556
    GO

    Sequence cautioni

    The sequence ACA11907.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000941 Genomic DNA. Translation: ACA11907.1. Different initiation.
    RefSeqiYP_001775537.1. NC_010513.1.

    Genome annotation databases

    EnsemblBacteriaiACA11907; ACA11907; Xfasm12_0929.
    GeneIDi6120788.
    KEGGixfm:Xfasm12_0929.
    PATRICi24138295. VBIXylFas124301_1103.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000941 Genomic DNA. Translation: ACA11907.1 . Different initiation.
    RefSeqi YP_001775537.1. NC_010513.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 405440.Xfasm12_0929.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACA11907 ; ACA11907 ; Xfasm12_0929 .
    GeneIDi 6120788.
    KEGGi xfm:Xfasm12_0929.
    PATRICi 24138295. VBIXylFas124301_1103.

    Phylogenomic databases

    eggNOGi COG1469.
    HOGENOMi HOG000247517.
    KOi K09007.
    OMAi AGRTTIQ.
    OrthoDBi EOG6X6RBH.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .
    BioCyci XFAS405440:GH0D-957-MONOMER.

    Family and domain databases

    HAMAPi MF_01527_B. GTP_cyclohydrol_B.
    InterProi IPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view ]
    Pfami PF02649. GCHY-1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequences of two Xylella fastidiosa strains (M12 and M23) causing almond leaf scorch disease in California."
      Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L.
      J. Bacteriol. 192:4534-4534(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: M12.

    Entry informationi

    Entry nameiGCH4_XYLFM
    AccessioniPrimary (citable) accession number: B0U741
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 5, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 45 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3