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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Xylella fastidiosa (strain M12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei74L-glutamineUniRule annotation1
Binding sitei218L-glutamineUniRule annotation1
Binding sitei237ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi42 – 44ATPUniRule annotation3
Nucleotide bindingi48 – 54ATPUniRule annotation7
Nucleotide bindingi285 – 286ATPUniRule annotation2
Nucleotide bindingi293 – 295ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:Xfasm12_0694
OrganismiXylella fastidiosa (strain M12)
Taxonomic identifieri405440 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000955181 – 580Glutamine--tRNA ligaseAdd BLAST580

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0U6D0
SMRiB0U6D0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi41 – 51"HIGH" regionUniRule annotationAdd BLAST11
Motifi292 – 296"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000259232
KOiK01886
OMAiVTHSICT

Family and domain databases

Gene3Di1.10.1160.101 hit
2.40.240.103 hits
3.40.50.6202 hits
HAMAPiMF_00126 Gln_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR004514 Gln-tRNA-synth
IPR022861 Gln_tRNA_ligase_bac
IPR000924 Glu/Gln-tRNA-synth
IPR020058 Glu/Gln-tRNA-synth_Ib_cat-dom
IPR020059 Glu/Gln-tRNA-synth_Ib_codon-bd
IPR020061 Glu_tRNA_lig_a-bdl
IPR020056 Rbsml_L25/Gln-tRNA_synth_N
IPR011035 Ribosomal_L25/Gln-tRNA_synth
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF00749 tRNA-synt_1c, 2 hits
PF03950 tRNA-synt_1c_C, 1 hit
PRINTSiPR00987 TRNASYNTHGLU
SUPFAMiSSF50715 SSF50715, 1 hit
TIGRFAMsiTIGR00440 glnS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B0U6D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEITTTDAQ AQPEKKDFIR QIIREDLAHG THTHIHTRFP PEPNGYLHIG
60 70 80 90 100
HAKAICLDFG VAAEFGGHCT LRMDDTNPSK EDPAFAAAIQ EDVSWLGFHW
110 120 130 140 150
NALRHTSDYF EVLYLAAEKL IADGKAYVCD LNSEQVREYR GTLTEAGRPS
160 170 180 190 200
PWRERSPDEN LELFRQMRAG TFPDGTRTLR AKIDMASGNI NLRDPALYRI
210 220 230 240 250
KHVEHQNTGN TWPIYPMYDF AHALSDAIEG ITHSLCTLEF EDHRPLYDWC
260 270 280 290 300
INHVDLPNNS HLLKPLLDKG FPQEPSQPRQ IEFSRLNINY TVMSKRKLTA
310 320 330 340 350
LVDEKLVEGW DDPRMYTLQG LRRRGYTPAA MRLFVERIGI SKQNSIIDFS
360 370 380 390 400
VLENCLRENL DTIAPRRMAT IAPMKLVLTN LPEDHEEQLI FPNHPKDDTQ
410 420 430 440 450
GTRTVPFSRE LWIERDDFSE VPPKGWKRLV PGGEVRLRGA GIARIDEVVK
460 470 480 490 500
NAEGHIIALH GWLDPTSRPG MEGAHRKVKG TIHWVSAPHA VAAEIRLYDR
510 520 530 540 550
LFSIEKPDDN TDGKTYRDFL NPDSKRVVHG YIEPAAAQTA PEHAFQFERL
560 570 580
GYFVTDRHDH DATHPVFNRS VTLRDTWQRD
Length:580
Mass (Da):66,417
Last modified:April 8, 2008 - v1
Checksum:iDD6F50E72551D321
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000941 Genomic DNA Translation: ACA11692.1
RefSeqiWP_004083872.1, NC_010513.1

Genome annotation databases

EnsemblBacteriaiACA11692; ACA11692; Xfasm12_0694
KEGGixfm:Xfasm12_0694

Similar proteinsi

Entry informationi

Entry nameiSYQ_XYLFM
AccessioniPrimary (citable) accession number: B0U6D0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: February 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program