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B0U6D0 (SYQ_XYLFM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:Xfasm12_0694
OrganismXylella fastidiosa (strain M12) [Complete proteome] [HAMAP]
Taxonomic identifier405440 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella

Protein attributes

Sequence length580 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 580580Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_1000095518

Regions

Motif41 – 5111"HIGH" region HAMAP-Rule MF_00126
Motif292 – 2965"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2951ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B0U6D0 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: DD6F50E72551D321

FASTA58066,417
        10         20         30         40         50         60 
MSEITTTDAQ AQPEKKDFIR QIIREDLAHG THTHIHTRFP PEPNGYLHIG HAKAICLDFG 

        70         80         90        100        110        120 
VAAEFGGHCT LRMDDTNPSK EDPAFAAAIQ EDVSWLGFHW NALRHTSDYF EVLYLAAEKL 

       130        140        150        160        170        180 
IADGKAYVCD LNSEQVREYR GTLTEAGRPS PWRERSPDEN LELFRQMRAG TFPDGTRTLR 

       190        200        210        220        230        240 
AKIDMASGNI NLRDPALYRI KHVEHQNTGN TWPIYPMYDF AHALSDAIEG ITHSLCTLEF 

       250        260        270        280        290        300 
EDHRPLYDWC INHVDLPNNS HLLKPLLDKG FPQEPSQPRQ IEFSRLNINY TVMSKRKLTA 

       310        320        330        340        350        360 
LVDEKLVEGW DDPRMYTLQG LRRRGYTPAA MRLFVERIGI SKQNSIIDFS VLENCLRENL 

       370        380        390        400        410        420 
DTIAPRRMAT IAPMKLVLTN LPEDHEEQLI FPNHPKDDTQ GTRTVPFSRE LWIERDDFSE 

       430        440        450        460        470        480 
VPPKGWKRLV PGGEVRLRGA GIARIDEVVK NAEGHIIALH GWLDPTSRPG MEGAHRKVKG 

       490        500        510        520        530        540 
TIHWVSAPHA VAAEIRLYDR LFSIEKPDDN TDGKTYRDFL NPDSKRVVHG YIEPAAAQTA 

       550        560        570        580 
PEHAFQFERL GYFVTDRHDH DATHPVFNRS VTLRDTWQRD 

« Hide

References

[1]"Whole genome sequences of two Xylella fastidiosa strains (M12 and M23) causing almond leaf scorch disease in California."
Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L.
J. Bacteriol. 192:4534-4534(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000941 Genomic DNA. Translation: ACA11692.1.
RefSeqYP_001775322.1. NC_010513.1.

3D structure databases

ProteinModelPortalB0U6D0.
SMRB0U6D0. Positions 17-576.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405440.Xfasm12_0694.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA11692; ACA11692; Xfasm12_0694.
GeneID6119379.
KEGGxfm:Xfasm12_0694.
PATRIC24137752. VBIXylFas124301_0833.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMAVTHSICT.
OrthoDBEOG6DRPF7.
ProtClustDBPRK05347.

Enzyme and pathway databases

BioCycXFAS405440:GH0D-722-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 2 hits.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_XYLFM
AccessionPrimary (citable) accession number: B0U6D0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: February 19, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries