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B0U6C7 (AROB_XYLFM) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:Xfasm12_0691
OrganismXylella fastidiosa (strain M12) [Complete proteome] [HAMAP]
Taxonomic identifier405440 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xylella

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3703703-dehydroquinate synthase HAMAP MF_00110
PRO_1000094657

Sequences

Sequence LengthMass (Da)Tools
B0U6C7 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 840322A1B88E5F5D

FASTA37039,435
        10         20         30         40         50         60 
MTTPTPLRSV TVNTPPPYTI AIGPGLLHDP PRLAATIRGR HALILSDSEV APRYAAQLHE 

        70         80         90        100        110        120 
TLLRARPDLH LNVFTLPAGE TSKSLENFGA AIAQLATLGA TRDACLFALG GGVIGDLTGF 

       130        140        150        160        170        180 
TAACWMRGID YVQVPTTLLA MVDSSVGGKT AVDIPQGKNM VGAFHPPRAV IADTDTLATL 

       190        200        210        220        230        240 
PLRELRAGLS EVIKYGAIRD PVFFHWLQTT REALLARDPA ALAQAIARSC EHKADIVGRD 

       250        260        270        280        290        300 
PLEKGERVLL NLGHTFGHAI ETTQGYSTPG SNNLNHGEAV AVGMVLAARL SNTLGLAPAE 

       310        320        330        340        350        360 
DTETLKNLLD AYGLPTVLPS GLKPETLLER MRLDKKNIAG RLRLVLWRGI GHAEAVPDVD 

       370 
EAAVRQILAN

« Hide

References

[1]"Whole genome sequences of two Xylella fastidiosa strains (M12 and M23) causing almond leaf scorch disease in California."
Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L.
J. Bacteriol. 192:4534-4534(2010) [PubMed: 20601474] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000941 Genomic DNA. Translation: ACA11689.1.
RefSeqYP_001775319.1. NC_010513.1.

3D structure databases

ProteinModelPortalB0U6C7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0U6C7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6119376.
GenomeReviewsGene locus Xfasm12_0691 in contig CP000941_GR.
KEGGxfm:Xfasm12_0691.
PATRIC24137744. VBIXylFas124301_0829.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAMADEHEQ.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycXFAS405440:XFASM12_0691-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_XYLFM
AccessionPrimary (citable) accession number: B0U6C7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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