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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Xylella fastidiosa (strain M12)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotationSAAS annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei46 – 461NucleophileUniRule annotation

GO - Molecular functioni

  1. lyase activity Source: UniProtKB-KW
  2. pseudouridine synthase activity Source: UniProtKB-HAMAP
  3. RNA binding Source: InterPro

GO - Biological processi

  1. RNA processing Source: InterPro
  2. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation, LyaseImported

Keywords - Biological processi

tRNA processingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciXFAS405440:GH0D-220-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotationSAAS annotation (EC:5.4.99.25UniRule annotationSAAS annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Xfasm12_0205Imported
OrganismiXylella fastidiosa (strain M12)Imported
Taxonomic identifieri405440 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
ProteomesiUP000008539 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi405440.Xfasm12_0205.

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231223.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

B0U1R0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRIAYRRLD GILLLDKPAG ISSNSALQVA RRLLRAKKGG HTGSLDPLAT
60 70 80 90 100
GLLPLCFGEA TKIAGLLLDS TKAYDADVLL GTTTTTDDAE GAVLLTRPVP
110 120 130 140 150
TLDAEMVDAL IPQLIGRIRQ RAPIYSALKQ GGEPLYVKAR RGEVVNAPVR
160 170 180 190 200
EVEVHAIELL VLATPRLQLR VTCGSGTYIR SLVRDLGEIL GCGAHITALR
210 220 230 240 250
RRWVAPFHIP KMLTLDSLEQ ALSAGRDPDS LLLPLVEGLA GFPALELDAQ
260 270 280 290 300
RLACFRLGQR LRDHSFQTGR VAVFSRDGIP AGLGEVDSEG LLVPQRLFNL
Length:300
Mass (Da):32,372
Last modified:April 8, 2008 - v1
Checksum:i33B2B071AA58691A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000941 Genomic DNA. Translation: ACA11238.1.
RefSeqiYP_001774868.1. NC_010513.1.

Genome annotation databases

EnsemblBacteriaiACA11238; ACA11238; Xfasm12_0205.
KEGGixfm:Xfasm12_0205.
PATRICi24136575. VBIXylFas124301_0254.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000941 Genomic DNA. Translation: ACA11238.1.
RefSeqiYP_001774868.1. NC_010513.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi405440.Xfasm12_0205.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA11238; ACA11238; Xfasm12_0205.
KEGGixfm:Xfasm12_0205.
PATRICi24136575. VBIXylFas124301_0254.

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231223.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Enzyme and pathway databases

BioCyciXFAS405440:GH0D-220-MONOMER.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Whole genome sequences of two Xylella fastidiosa strains (M12 and M23) causing almond leaf scorch disease in California."
    Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L.
    J. Bacteriol. 192:4534-4534(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M12Imported.

Entry informationi

Entry nameiB0U1R0_XYLFM
AccessioniPrimary (citable) accession number: B0U1R0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 1, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.