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Protein

Beta-galactosidase

Gene

Fphi_0309

Organism
Francisella philomiragia subsp. philomiragia (strain ATCC 25017)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei103 – 1031SubstrateUniRule annotation
Metal bindingi107 – 1071ZincUniRule annotation
Binding sitei141 – 1411SubstrateUniRule annotation
Active sitei142 – 1421Proton donorUniRule annotation
Metal bindingi151 – 1511ZincUniRule annotation
Metal bindingi153 – 1531ZincUniRule annotation
Metal bindingi156 – 1561ZincUniRule annotation
Active sitei304 – 3041NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciFPHI484022:GHVB-307-MONOMER.

Protein family/group databases

CAZyiGH42. Glycoside Hydrolase Family 42.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Short name:
Beta-galUniRule annotation
Gene namesi
Ordered Locus Names:Fphi_0309Imported
OrganismiFrancisella philomiragia subsp. philomiragia (strain ATCC 25017)Imported
Taxonomic identifieri484022 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000001320 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi484022.Fphi_0309.

Structurei

3D structure databases

ProteinModelPortaliB0TZ86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 42 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1874.
HOGENOMiHOG000117811.
KOiK12308.
OMAiMLGVCYY.
OrthoDBiEOG6HMX9F.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

B0TZ86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFGVDYYPE QWDYSLIDDD LNRIADSELN CIRIAEFAWH LMEPRENEFD
60 70 80 90 100
FSFFEMILNK AHKLGLKVML GTPTATVPAW LYKKDPKVFS VDENGLQRHF
110 120 130 140 150
GGRRQACLNS PTYNKYAERI TQKMVEAYHK HPALLLWHID NELGHETSDM
160 170 180 190 200
CYCNQCELEF RNYLKEVFNN DINSFNDAIG SVFWSQTYNN FDEINIPRPT
210 220 230 240 250
IPAPNPGMML YFNRFRAQTT TNFLARQAKV IKEIVPNQQT LHNFTGDYFS
260 270 280 290 300
KAQDHTDLAE QIDIVALNNY PVWGGQQIPV NAYKTAMKLD QTRGFQRRNY
310 320 330 340 350
WITEQLIGAQ AHNIMGFVPR PGHAKLWSFQ AMARGCENLI YFRWRTATKG
360 370 380 390 400
AEQFCYGVLD HDNKYNHRYN EMLDIIKLAK QNQQAIQAPT QSKVALLYSM
410 420 430 440 450
DNIYSWRIQQ QSTAFNIQHE HARLYKPFFD ANISVDVLDI RHNFSSYSVL
460 470 480 490 500
LLPVAMLITD ENIARIKTFI ENGGIVIATF RAGLKEYHNE IRFGVENPIH
510 520 530 540 550
ELAGVKAEYF EPLPMGTDCK IKYQDKDLTA TVWRDMLTVK EPCKSLCNYI
560 570 580 590 600
DEFKNYSAAV KNKVGKGEIY YIGTGIDDEY FWNDLVLDLA KKHNLDTYSS
610 620 630 640 650
PSDIEIVIKG EKDSKIAIIL NHNRNEIEYL GLKLKAYDTQ ILKYLEFYEL

YSKYY
Length:655
Mass (Da):76,380
Last modified:April 8, 2008 - v1
Checksum:i6BE07052D3BD285D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000937 Genomic DNA. Translation: ABZ86525.1.
RefSeqiWP_012279809.1. NC_010336.1.

Genome annotation databases

EnsemblBacteriaiABZ86525; ABZ86525; Fphi_0309.
KEGGifph:Fphi_0309.
PATRICi17937417. VBIFraPhi43880_0318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000937 Genomic DNA. Translation: ABZ86525.1.
RefSeqiWP_012279809.1. NC_010336.1.

3D structure databases

ProteinModelPortaliB0TZ86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi484022.Fphi_0309.

Protein family/group databases

CAZyiGH42. Glycoside Hydrolase Family 42.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABZ86525; ABZ86525; Fphi_0309.
KEGGifph:Fphi_0309.
PATRICi17937417. VBIFraPhi43880_0318.

Phylogenomic databases

eggNOGiCOG1874.
HOGENOMiHOG000117811.
KOiK12308.
OMAiMLGVCYY.
OrthoDBiEOG6HMX9F.

Enzyme and pathway databases

BioCyciFPHI484022:GHVB-307-MONOMER.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Francisella philomiragia subsp. philomiragia ATCC 25017."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Richardson P.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25017Imported.

Entry informationi

Entry nameiB0TZ86_FRAP2
AccessioniPrimary (citable) accession number: B0TZ86
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: July 22, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.