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B0TZ61 (B0TZ61_FRAP2) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515
Gene names
Ordered Locus Names:Fphi_0284 EMBL ABZ86500.1
OrganismFrancisella philomiragia subsp. philomiragia (strain ATCC 25017) [Complete proteome] [HAMAP] EMBL ABZ86500.1
Taxonomic identifier484022 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella ›

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. PIRSR PIRSR001415-3 RuleBase RU000515

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1961Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2481Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1201Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1221Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1301Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding2331Magnesium By similarity PIRSR PIRSR001415-5
Binding site2061Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2171Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2741Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3131Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
B0TZ61 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: F39BB6087F765C68

FASTA32335,954
        10         20         30         40         50         60 
MSFPISRPRR LRVTQAFRDM VAETKLNIDD LMYPIFVVHG NGIKKEISSM PNQYHWSVDM 

        70         80         90        100        110        120 
LDELVEQVIK LGIKSLMIFG VPKTKDLISS ENYDPNGITQ QAIRKIKQLA PELVVATDVC 

       130        140        150        160        170        180 
MCSFTPHGHC GILDEHDYVD NDRTLEILQK TAISHAQAGA DIVAPSGMMD GMIIAMRQAL 

       190        200        210        220        230        240 
DESGFETVSI MSYSVKYASA YYGPFRSACS SSLKGDRKTY QMDYRNKKEA IREALADVEQ 

       250        260        270        280        290        300 
GADFIMVKPA LSYLDIINEL SHIIELPIAA YHVSGEYAMI KAAANAGLVD EKAITIETLT 

       310        320 
SMKRAGAKII LTYTALDVAN WIR

« Hide

References

[1]"Complete sequence of chromosome of Francisella philomiragia subsp. philomiragia ATCC 25017."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Richardson P.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25017.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000937 Genomic DNA. Translation: ABZ86500.1.
RefSeqYP_001677001.1. NC_010336.1.

3D structure databases

ProteinModelPortalB0TZ61.
SMRB0TZ61. Positions 5-320.
ModBaseSearch...

Protein-protein interaction databases

STRING484022.Fphi_0284.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABZ86500; ABZ86500; Fphi_0284.
GeneID5908104.
KEGGfph:Fphi_0284.
PATRIC17937367. VBIFraPhi43880_0293.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0113.
HOGENOMHOG000020323.
KOK01698.
OMAMIISYHA.
ProtClustDBPRK09283.

Enzyme and pathway databases

BioCycFPHI484022:GHVB-282-MONOMER.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
PANTHERPTHR11458. PTHR11458. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0TZ61_FRAP2
AccessionPrimary (citable) accession number: B0TZ61
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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