B0TXC3 (B0TXC3_FRAP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-O-acyl-N-acetylglucosamine deacetylase EMBL ABZ87381.1

Gene names

Ordered Locus Names:

Fphi_1157

Organism

Francisella philomiragia subsp. philomiragia (strain ATCC 25017) [Complete proteome] [HAMAP]

Taxonomic identifier

484022 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0TXC3 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: E972C663CF03F657	FASTA	283	32,017
	10 20 30 40 50 60 MQYTLTNPVY ISGKGLHTNR YNTIIISPAP ADTGIVFCIS GKAIPTHYSH VIDKPLCTCI 70 80 90 100 110 120 ATDEQHYIRT IEHLLAALFC IGIDNAYIYS QTNEIPILDG SCNGFYQQLQ LAGIQQNNSP 130 140 150 160 170 180 VKKLIIKKTI EYRQGNRYIK VSPNDDFSIH LQIKPKCGYQ NYNKIITPEV LISDCIDART 190 200 210 220 230 240 FGPLYKGILA KVLTKFSKTP VAQGASTHNT ILLTKKKSYV KNSLRYTDEH VRHRVMDLVG 250 260 270 280 DLMLCGTRHI SGHFETYSTS HAMNAKLLEK IFVDQSNFEW QEI

References

[1]

"Complete sequence of chromosome of Francisella philomiragia subsp. philomiragia ATCC 25017." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25017.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000937 Genomic DNA. Translation: ABZ87381.1.
RefSeq	YP_001677882.1. NC_010336.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B0TXC3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5907116.
GenomeReviews	Gene locus Fphi_1157 in contig CP000937_GR.
KEGG	fph:Fphi_1157.
PATRIC	17939240. VBIFraPhi43880_1203.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG482342.
OMA	IAFRRVA.
ProtClustDB	PRK13186.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMs	TIGR00325. LpxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0TXC3_FRAP2

Accession

Primary (citable) accession number: B0TXC3

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)