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Protein

Glutamate decarboxylase

Gene

Fphi_0903

Organism
Francisella philomiragia subsp. philomiragia (strain ATCC 25017)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciFPHI484022:GHVB-926-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Fphi_0903Imported
OrganismiFrancisella philomiragia subsp. philomiragia (strain ATCC 25017)Imported
Taxonomic identifieri484022 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000001320 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi484022.Fphi_0903.

Structurei

3D structure databases

ProteinModelPortaliB0TWL8.
SMRiB0TWL8. Positions 12-434.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiERQTGID.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

B0TWL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALHAKNDMK HKLYKESLPK FEIPKKSNDA FEAYQQIKDE LMLDGNSKQN
60 70 80 90 100
LATFCQTEVD DFIHRLMDDC IDKNMIDKDE YPQTAEIESR CVNILANLWN
110 120 130 140 150
SSAENAIGCS TTGSSEAAML GGMAMKWRWR DKMKAQGKDY TKPNLVTGPV
160 170 180 190 200
QVCWHKFARY WDIELREIPM SNESLIMTPE TMLKYCDENT IGVVPTLGVT
210 220 230 240 250
FTGQYEPVEA VCEALDKFER DTGIDIPVHV DAASGGFLAP FVEPELKWDF
260 270 280 290 300
RLPRVKSINS SGHKFGLSPL GVGWVVWADK KYLPQDLIFN VNYLGGDMPT
310 320 330 340 350
FALNFSRPGG QIVAQYYNFV KLGFEGYKNI HKLSYDVAKY IAKEIKDMGI
360 370 380 390 400
FDIIHAGKGG IPAVSWSLKA GKSYDLFDIS EKIRARGWQI AAYSMPKDRQ
410 420 430 440
DLVVMRVLVR RGFSFDLAEL MIRDLKNVIN SLDNKSKDIE RGGFSH
Length:446
Mass (Da):50,556
Last modified:April 7, 2008 - v1
Checksum:i256DE222E5C4768F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000937 Genomic DNA. Translation: ABZ87126.1.
RefSeqiYP_001677627.1. NC_010336.1.

Genome annotation databases

EnsemblBacteriaiABZ87126; ABZ87126; Fphi_0903.
KEGGifph:Fphi_0903.
PATRICi17938698. VBIFraPhi43880_0941.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000937 Genomic DNA. Translation: ABZ87126.1.
RefSeqiYP_001677627.1. NC_010336.1.

3D structure databases

ProteinModelPortaliB0TWL8.
SMRiB0TWL8. Positions 12-434.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi484022.Fphi_0903.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABZ87126; ABZ87126; Fphi_0903.
KEGGifph:Fphi_0903.
PATRICi17938698. VBIFraPhi43880_0941.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiERQTGID.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciFPHI484022:GHVB-926-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Francisella philomiragia subsp. philomiragia ATCC 25017."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Richardson P.
    Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25017Imported.

Entry informationi

Entry nameiB0TWL8_FRAP2
AccessioniPrimary (citable) accession number: B0TWL8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 7, 2008
Last sequence update: April 7, 2008
Last modified: March 31, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.