SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B0TPW7

- PUR5_SHEHH

UniProt

B0TPW7 - PUR5_SHEHH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, Shal_1680
Organism
Shewanella halifaxensis (strain HAW-EB4)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSHAL458817:GH1X-1732-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:Shal_1680
OrganismiShewanella halifaxensis (strain HAW-EB4)
Taxonomic identifieri458817 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001317: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_1000148295Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi458817.Shal_1680.

Structurei

3D structure databases

ProteinModelPortaliB0TPW7.
SMRiB0TPW7. Positions 6-343.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

B0TPW7-1 [UniParc]FASTAAdd to Basket

« Hide

MSTPTTPLSY KDAGVDIDAG NALVNNIKSA VKRTRRPEVM GNLGGFGALC    50
ELPTKYKHPV LVSGTDGVGT KLRLAIDFKK HDNVGIDLVA MCSNDLIVSG 100
AEPLFFLDYY ATGKLDVEVA TAVVKGIAEG CVQSGCALIG GETAEMPGMY 150
EGDDYDLAGF CVGVVEKEEI IDGTKVQDGD ALIALASSGP HSNGFSLIRK 200
VLEVSKADPE LELAGKPLID HLLEPTKIYV KSLLKLLEQH DVHAMSHITG 250
GGFWENIPRV LPEDCKAVVN SDSWQWPVVF NWLMENGNIS EFEMYRTFNC 300
GVGMVIALPA DKVDSALALL KTEGENAWLI GNIAKRNGEE EQVEIL 346
Length:346
Mass (Da):37,295
Last modified:April 8, 2008 - v1
Checksum:iDA8E17AA69A91986
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000931 Genomic DNA. Translation: ABZ76246.1.
RefSeqiYP_001673905.1. NC_010334.1.

Genome annotation databases

EnsemblBacteriaiABZ76246; ABZ76246; Shal_1680.
GeneIDi5902613.
KEGGishl:Shal_1680.
PATRICi23506016. VBISheHal24697_1766.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000931 Genomic DNA. Translation: ABZ76246.1 .
RefSeqi YP_001673905.1. NC_010334.1.

3D structure databases

ProteinModelPortali B0TPW7.
SMRi B0TPW7. Positions 6-343.
ModBasei Search...

Protein-protein interaction databases

STRINGi 458817.Shal_1680.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABZ76246 ; ABZ76246 ; Shal_1680 .
GeneIDi 5902613.
KEGGi shl:Shal_1680.
PATRICi 23506016. VBISheHal24697_1766.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci SHAL458817:GH1X-1732-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HAW-EB4.

Entry informationi

Entry nameiPUR5_SHEHH
AccessioniPrimary (citable) accession number: B0TPW7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: April 8, 2008
Last modified: May 14, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi