ID   PYRB3_SHEHH             Reviewed;         310 AA.
AC   B0TPF3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   05-MAY-2009, entry version 10.
DE   RecName: Full=Aspartate carbamoyltransferase 3;
DE            EC=2.1.3.2;
DE   AltName: Full=Aspartate transcarbamylase 3;
DE            Short=ATCase 3;
GN   Name=pyrB3; OrderedLocusNames=Shal_3052;
OS   Shewanella halifaxensis (strain HAW-EB4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=458817;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella halifaxensis HAW-EB4.";
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate
CC       + N-carbamoyl-L-aspartate.
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC       pathway; UMP from HCO(3)(-): step 2/6.
CC   -!- SIMILARITY: Belongs to the ATCase/OTCase family.
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DR   EMBL; CP000931; ABZ77600.1; -; Genomic_DNA.
DR   RefSeq; YP_001675259.1; -.
DR   GeneID; 5906713; -.
DR   GenomeReviews; CP000931_GR; Shal_3052.
DR   KEGG; shl:Shal_3052; -.
DR   OMA; B0TPF3; RIQRERI.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0004070; F:aspartate carbamoyltransferase activity; IEA:HAMAP.
DR   GO; GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00001; -; 1.
DR   InterPro; IPR006132; Asp/Orn_carbamoyltranf_P_bd.
DR   InterPro; IPR006130; Asp/Orn_carbamoylTrfase.
DR   InterPro; IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
DR   InterPro; IPR002082; Aspartate_carbamoyltransf_euk.
DR   Pfam; PF00185; OTCace; 1.
DR   Pfam; PF02729; OTCace_N; 1.
DR   PRINTS; PR00100; AOTCASE.
DR   PRINTS; PR00101; ATCASE.
DR   TIGRFAMs; TIGR00670; asp_carb_tr; 1.
DR   PROSITE; PS00097; CARBAMOYLTRANSFERASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Pyrimidine biosynthesis; Transferase.
FT   CHAIN         1    310       Aspartate carbamoyltransferase 3.
FT                                /FTId=PRO_0000334595.
SQ   SEQUENCE   310 AA;  34541 MW;  201E82B83C426B82 CRC64;
     MSNPIYNKHI ISISDLSRSE LELIVSTAND LKQNPRPDLL KNKVVASCFF EASTRTRLSF
     ETAVQRLGGS VIGFPDSGNT SLGKKGETLA DSVQVISSYC DAFFMRHNQE GAARLASEFS
     SAPVINGGDG SNQHPTQTLL DLFSIYETQG TLEKLQVAFV GDLKYGRTVH SLTQALSLFD
     CEFHFIAPAA LSMPDYIIDE LKAKGCKYTL HDHLDGVLPN LDILYMTRVQ KERFDETEYQ
     HLKSSFILNA NMLEGVKENL KVLHPLPRID EITTDVDSTP YAYYFQQAKN GVYARQALLA
     LVLTNEFGDK
//