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B0TL85

- ASSY_SHEHH

UniProt

B0TL85 - ASSY_SHEHH

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Protein

Argininosuccinate synthase

Gene
argG, Shal_4090
Organism
Shewanella halifaxensis (strain HAW-EB4)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei48 – 481ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei100 – 1001Citrulline By similarity
Binding sitei105 – 1051Citrulline By similarity
Binding sitei130 – 1301ATP; via amide nitrogen By similarity
Binding sitei132 – 1321Aspartate By similarity
Binding sitei136 – 1361Aspartate By similarity
Binding sitei136 – 1361Citrulline By similarity
Binding sitei137 – 1371Aspartate By similarity
Binding sitei140 – 1401Citrulline By similarity
Binding sitei189 – 1891Citrulline By similarity
Binding sitei198 – 1981Citrulline By similarity
Binding sitei274 – 2741Citrulline By similarity
Binding sitei286 – 2861Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 289ATP By similarity

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSHAL458817:GH1X-4223-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:Shal_4090
OrganismiShewanella halifaxensis (strain HAW-EB4)
Taxonomic identifieri458817 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001317: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 412412Argininosuccinate synthaseUniRule annotationPRO_1000073830Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi458817.Shal_4090.

Structurei

3D structure databases

ProteinModelPortaliB0TL85.
SMRiB0TL85. Positions 16-411.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiPECEYIR.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0TL85-1 [UniParc]FASTAAdd to Basket

« Hide

MSNENSAVTK HAGVKKVVLA YSGGLDTSAI IPWLKETYDD CEIIAFCADV    50
GQGDAELEGL YEKAIASGAS ECHIVDLKEE LVADYIYPTI ATGAIYEGTY 100
LLGTSMARPI IAKAQVEVAR KVGADAVCHG CTGKGNDQVR FEGCFAALAP 150
DLKVIAPWRE WEMVSREDLL DYLAERNIAT SASATKIYSR DANAWHISHE 200
GGELEDPWNE PSKGVWTMTV APEDAPNQPE YVALELEQGK ITKVNGEALS 250
PYNALMLLNE VAGAHGVGRI DITENRLVGM KSRGCYETPG GTVMFAALRA 300
IEELVLDKTS REWREQIGTK MAHLVYDGRW FTPLCESLLG ASKPLADLIN 350
GEVVVKLYKG QASVVKKRSP NSLYSEAFAT FGADDVYNQK DAEGFIRLYS 400
LSSRIRALNN QK 412
Length:412
Mass (Da):44,998
Last modified:April 8, 2008 - v1
Checksum:iCCC149FE4CFB363D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000931 Genomic DNA. Translation: ABZ78630.1.
RefSeqiYP_001676289.1. NC_010334.1.

Genome annotation databases

EnsemblBacteriaiABZ78630; ABZ78630; Shal_4090.
GeneIDi5902889.
KEGGishl:Shal_4090.
PATRICi23511220. VBISheHal24697_4283.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000931 Genomic DNA. Translation: ABZ78630.1 .
RefSeqi YP_001676289.1. NC_010334.1.

3D structure databases

ProteinModelPortali B0TL85.
SMRi B0TL85. Positions 16-411.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 458817.Shal_4090.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABZ78630 ; ABZ78630 ; Shal_4090 .
GeneIDi 5902889.
KEGGi shl:Shal_4090.
PATRICi 23511220. VBISheHal24697_4283.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi PECEYIR.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci SHAL458817:GH1X-4223-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HAW-EB4.

Entry informationi

Entry nameiASSY_SHEHH
AccessioniPrimary (citable) accession number: B0TL85
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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