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B0TJD3

- TRMB_SHEHH

UniProt

B0TJD3 - TRMB_SHEHH

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, Shal_1155
Organism
Shewanella halifaxensis (strain HAW-EB4)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei68 – 681S-adenosyl-L-methionine By similarity
Binding sitei93 – 931S-adenosyl-L-methionine By similarity
Binding sitei120 – 1201S-adenosyl-L-methionine By similarity
Active sitei143 – 1431 By similarity
Binding sitei143 – 1431S-adenosyl-L-methionine By similarity
Binding sitei147 – 1471Substrate By similarity
Binding sitei179 – 1791Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciSHAL458817:GH1X-1175-MONOMER.
    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferase
    tRNA(m7G46)-methyltransferase
    Gene namesi
    Name:trmB
    Ordered Locus Names:Shal_1155
    OrganismiShewanella halifaxensis (strain HAW-EB4)
    Taxonomic identifieri458817 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000001317: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 237237tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
    PRO_1000084450Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi458817.Shal_1155.

    Structurei

    3D structure databases

    ProteinModelPortaliB0TJD3.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni216 – 2194Substrate binding By similarity

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0220.
    HOGENOMiHOG000073968.
    KOiK03439.
    OMAiTSATNDY.
    OrthoDBiEOG6K6VBC.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0TJD3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDVTTAEFN EEGKYLRKVR SFVLREGRLT KGQAQAMEQQ WPIMGLDYTP    50
    ESIDLVEVFG READTVLEIG FGMGASLVAM AKASPELNFI GIEVHKPGVG 100
    ACLAEAAEAG VTNLRVYHHD AIEVLENSIA EGSLACVQLF FPDPWHKTRH 150
    HKRRIVQAPF AELIRSKLKV GGVFHLATDW ENYSEHMLEV MNAAPGYKNQ 200
    SATGDVVERP DHRPLTKFEA RGHRLGHGVW DLMFERV 237
    Length:237
    Mass (Da):26,523
    Last modified:April 8, 2008 - v1
    Checksum:i3AC1880564CE7C1F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000931 Genomic DNA. Translation: ABZ75724.1.
    RefSeqiWP_012276267.1. NC_010334.1.
    YP_001673383.1. NC_010334.1.

    Genome annotation databases

    EnsemblBacteriaiABZ75724; ABZ75724; Shal_1155.
    GeneIDi5905707.
    KEGGishl:Shal_1155.
    PATRICi23504858. VBISheHal24697_1218.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000931 Genomic DNA. Translation: ABZ75724.1 .
    RefSeqi WP_012276267.1. NC_010334.1.
    YP_001673383.1. NC_010334.1.

    3D structure databases

    ProteinModelPortali B0TJD3.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 458817.Shal_1155.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABZ75724 ; ABZ75724 ; Shal_1155 .
    GeneIDi 5905707.
    KEGGi shl:Shal_1155.
    PATRICi 23504858. VBISheHal24697_1218.

    Phylogenomic databases

    eggNOGi COG0220.
    HOGENOMi HOG000073968.
    KOi K03439.
    OMAi TSATNDY.
    OrthoDBi EOG6K6VBC.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .
    BioCyci SHAL458817:GH1X-1175-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HAW-EB4.

    Entry informationi

    Entry nameiTRMB_SHEHH
    AccessioniPrimary (citable) accession number: B0TJD3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: April 8, 2008
    Last modified: September 3, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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