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B0THS7 (B0THS7_HELMI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase HAMAP MF_00102
Short name=DHPR HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB HAMAP MF_00102 EMBL ABZ84860.1
Ordered Locus Names:Helmi_22350
ORF Names:HM1_2327 EMBL ABZ84860.1
OrganismHeliobacterium modesticaldum (strain ATCC 51547 / Ice1) [Complete proteome] [HAMAP]
Taxonomic identifier498761 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Heliobacteriaceae › Heliobacterium

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102 SAAS SAAS022664

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102 SAAS SAAS022664

Subcellular location

Cytoplasm By similarity HAMAP MF_00102 SAAS SAAS022664.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
B0THS7 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 8B4062F87D85D21C

FASTA26728,684
        10         20         30         40         50         60 
MSERIRVLVS GARGKVGREV IKAVLGDNTL ELVAAVDHNG VGEDAAVLAG LPACGVLIQG 

        70         80         90        100        110        120 
DLAAAITETQ PQVMVDFTSP ASVMENVRIA LMAGVAPVVG TTGLSARDME EIAEWAAAKE 

       130        140        150        160        170        180 
VGCLIAPNFA IGALLMMRFA REAARFFPNV EIIEYHHDQK LDAPSGTAIK TAELIREERR 

       190        200        210        220        230        240 
AIRQGHPEEE EKITGSRGGE FDGMRIHSVR LPGLVAHQEV IFGALGQTLS IRHDSISRES 

       250        260 
FMPGVLEAIH RIGAYKGLIY GLDKIIF

« Hide

References

[1]"The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus."
Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M., Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W.
J. Bacteriol. 190:4687-4696(2008) [PubMed: 18441057] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000930 Genomic DNA. Translation: ABZ84860.1.
RefSeqYP_001680871.1. NC_010337.2.

3D structure databases

ProteinModelPortalB0THS7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0THS7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5909522.
GenomeReviewsGene locus Helmi_22350 in contig CP000930_GR.
KEGGhmo:HM1_2327.
PATRIC22108711. VBIHelMod36755_2093.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG594002.
OMADRASFMP.
ProtClustDBPRK00048.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0THS7_HELMI
AccessionPrimary (citable) accession number: B0THS7
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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