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B0TGL6

- G6PI_HELMI

UniProt

B0TGL6 - G6PI_HELMI

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Heliobacterium modesticaldum (strain ATCC 51547 / Ice1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei308 – 3081UniRule annotation
Active sitei422 – 4221UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciHMOD498761:GI46-671-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Helmi_06520
ORF Names:HM1_1300
OrganismiHeliobacterium modesticaldum (strain ATCC 51547 / Ice1)
Taxonomic identifieri498761 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesHeliobacteriaceaeHeliobacterium
ProteomesiUP000008550: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 447447Glucose-6-phosphate isomerasePRO_1000125729Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi498761.HM1_1300.

Structurei

3D structure databases

ProteinModelPortaliB0TGL6.
SMRiB0TGL6. Positions 14-445.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiGVESYKR.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0TGL6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSLRLDLAY ATVESAISTM EDPIRQAHDL LHNRTGAGSE FTGWLQLPKT
60 70 80 90 100
YDRAEFARII DAADRIRASS DVLLVIGIGG SYLGARAAID MLSHSFHNQL
110 120 130 140 150
PRSRRPGCAV LFAGHNISSA YLSDLFDILD GKDVSVNVIS KSGTTTEPAI
160 170 180 190 200
AFRLIRRWME KKYSPDEVRR RIFATTDRAK GALKRLADEQ GYETFVVPDD
210 220 230 240 250
VGGRFSVLTT VGLLPIAAAG IDITALLAGA RDAMAEYANP SLATNACYRY
260 270 280 290 300
AAARNLLYRQ GKQVELFVAY EPSLQHLAEW WKQLYGESEG KEGKGIFPAS
310 320 330 340 350
VLFSTDLHSM GQYIQEGQRM LMETVVRFDK PRRELTIPPA EDDSDGLNFL
360 370 380 390 400
AGKTVDFVNQ KAFAGTLLAH VDGQVPNMII SVPEQNAYHL GQLFYFFEKA
410 420 430 440
CGVSGYLLGV NPFDQPGVES YKRNMFALLG KPGFEKEKAA LEARLPR
Length:447
Mass (Da):49,388
Last modified:April 8, 2008 - v1
Checksum:i6BD8C746225ACD06
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000930 Genomic DNA. Translation: ABZ83277.1.
RefSeqiWP_012281811.1. NC_010337.2.
YP_001679288.1. NC_010337.2.

Genome annotation databases

EnsemblBacteriaiABZ83277; ABZ83277; HM1_1300.
GeneIDi5910819.
KEGGihmo:HM1_1300.
PATRICi22105575. VBIHelMod36755_0589.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000930 Genomic DNA. Translation: ABZ83277.1 .
RefSeqi WP_012281811.1. NC_010337.2.
YP_001679288.1. NC_010337.2.

3D structure databases

ProteinModelPortali B0TGL6.
SMRi B0TGL6. Positions 14-445.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 498761.HM1_1300.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABZ83277 ; ABZ83277 ; HM1_1300 .
GeneIDi 5910819.
KEGGi hmo:HM1_1300.
PATRICi 22105575. VBIHelMod36755_0589.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi GVESYKR.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci HMOD498761:GI46-671-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus."
    Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M., Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W.
    J. Bacteriol. 190:4687-4696(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51547 / Ice1.

Entry informationi

Entry nameiG6PI_HELMI
AccessioniPrimary (citable) accession number: B0TGL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3