Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Heliobacterium modesticaldum (strain ATCC 51547 / Ice1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
ORF Names:HM1_2064Imported
OrganismiHeliobacterium modesticaldum (strain ATCC 51547 / Ice1)Imported
Taxonomic identifieri498761 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesHeliobacteriaceaeHeliobacterium
Proteomesi
  • UP000008550 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi498761.HM1_2064.

Structurei

3D structure databases

ProteinModelPortaliB0TGC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 205TubulinInterPro annotationAdd BLAST193
Domaini207 – 324Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B0TGC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFELDVDLNP LAVIRVVGVG GGGNNAVNRM ISHGVRGVQF VSVNTDAQAL
60 70 80 90 100
HLSRAETKMQ IGLKLTKGLG AGANPDIGKK AAEESREELI NALKGADMVF
110 120 130 140 150
VTAGMGGGTG TGAAPVVAEV ARELGALTVG VVTRPFTFEG RKRAMQAERG
160 170 180 190 200
ISELRAAVDT LIVIPNDRLL QVVDKHTPMN EAFRLADDIL RQGVQGISDL
210 220 230 240 250
IAVPGLINLD FADVKTIMSD TGSALMGVGY ASGEHRAIDA VKKAISSPLL
260 270 280 290 300
ETSIEGAKGV LMNITGGINL GMLEVNEAAE IVTEVADPEA NIIFGAVIDD
310 320 330 340 350
SMEDEVRVTV IATGFDHRHA QPAPKETMRV TSPVKDRYTQ PVVQQPTMEV
360 370
KPVPLGDDVD IPVFLRKYRG
Length:370
Mass (Da):39,189
Last modified:April 8, 2008 - v1
Checksum:i52160853FBB0C9EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000930 Genomic DNA. Translation: ABZ84621.1.
RefSeqiWP_012283121.1. NC_010337.2.

Genome annotation databases

EnsemblBacteriaiABZ84621; ABZ84621; HM1_2064.
KEGGihmo:HM1_2064.

Similar proteinsi

Entry informationi

Entry nameiB0TGC5_HELMI
AccessioniPrimary (citable) accession number: B0TGC5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: September 27, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported