B0TBV7 (B0TBV7_HELMI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable nicotinate-nucleotide adenylyltransferase HAMAP-Rule MF_00244
EC=2.7.7.18 HAMAP-Rule MF_00244

Alternative name(s):
Deamido-NAD(+) diphosphorylase HAMAP-Rule MF_00244
Deamido-NAD(+) pyrophosphorylase HAMAP-Rule MF_00244
Nicotinate mononucleotide adenylyltransferase HAMAP-Rule MF_00244

Gene names

Name:	nadD HAMAP-Rule MF_00244 EMBL ABZ85230.1
ORF Names:	HM1_2701 EMBL ABZ85230.1

Organism

Heliobacterium modesticaldum (strain ATCC 51547 / Ice1) [Complete proteome] [HAMAP] EMBL ABZ85230.1

Taxonomic identifier

498761 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Heliobacteriaceae › Heliobacterium › Heliobacterium modesticaldum

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) By similarity. HAMAP-Rule MF_00244
Catalytic activity	ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD+. HAMAP-Rule MF_00244 SAAS SAAS005248
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1. HAMAP-Rule MF_00244
Sequence similarities	Belongs to the NadD family. HAMAP-Rule MF_00244

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis HAMAP-Rule MF_00244 SAAS SAAS005248
Ligand	ATP-binding HAMAP-Rule MF_00244 SAAS SAAS005248 NAD HAMAP-Rule MF_00244 SAAS SAAS005248 Nucleotide-binding
Molecular function	Nucleotidyltransferase HAMAP-Rule MF_00244 SAAS SAAS005248 EMBL ABZ85230.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	NAD biosynthetic process Inferred from electronic annotation. Source: UniProtKB-HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW nicotinate-nucleotide adenylyltransferase activity Inferred from electronic annotation. Source: UniProtKB-HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0TBV7 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 17192F8591BEE002	FASTA	210	24,237
	10 20 30 40 50 60 MVRVGIMGGT FDPVHYGHLV TAEAAADLFD LSVVVFVPSG RPPHKQHQDV TDPWERYRLT 70 80 90 100 110 120 ELATCSNPRF RMSDVEVIRP GYSYTIDTVR AFRREYGEQA EFFFITGADA ILEIMTWRQI 130 140 150 160 170 180 DQLMAECRFI AAYRPGYGRD HLRKAVARME AFSGRIHLVE VPALAISSTD IRRRLYEGRS 190 200 210 VKYLLPEPVL HRIMETGVYH LASRHRQPRE

References

[1]

"The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus." Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M., Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W. J. Bacteriol. 190:4687-4696(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51547 / Ice1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000930 Genomic DNA. Translation: ABZ85230.1.
RefSeq	YP_001681241.1. NC_010337.2.
3D structure databases
ProteinModelPortal	B0TBV7.
ModBase	Search...
MobiDB	Search...
Protein-protein interaction databases
STRING	498761.HM1_2701.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABZ85230; ABZ85230; HM1_2701.
GeneID	5909809.
KEGG	hmo:HM1_2701.
PATRIC	22109437. VBIHelMod36755_2422.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1057.
HOGENOM	HOG000262779.
KO	K00969.
OMA	HYGHLRP.
OrthoDB	EOG6F55KJ.
Enzyme and pathway databases
BioCyc	HMOD498761:GI46-2716-MONOMER.
UniPathway	UPA00253; UER00332.
Family and domain databases
Gene3D	3.40.50.620. 1 hit.
HAMAP	MF_00244. NaMN_adenylyltr.
InterPro	IPR004821. Cyt_trans-like. IPR005248. NAMN_adtrnsfrase. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
PANTHER	PTHR12039. PTHR12039. 1 hit.
Pfam	PF01467. CTP_transf_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00125. cyt_tran_rel. 1 hit. TIGR00482. TIGR00482. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0TBV7_HELMI

Accession

Primary (citable) accession number: B0TBV7

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)