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B0TBV7 (B0TBV7_HELMI) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable nicotinate-nucleotide adenylyltransferase HAMAP-Rule MF_00244

EC=2.7.7.18 HAMAP-Rule MF_00244
Alternative name(s):
Deamido-NAD(+) diphosphorylase HAMAP-Rule MF_00244
Deamido-NAD(+) pyrophosphorylase HAMAP-Rule MF_00244
Nicotinate mononucleotide adenylyltransferase HAMAP-Rule MF_00244
Gene names
Name:nadD HAMAP-Rule MF_00244 EMBL ABZ85230.1
ORF Names:HM1_2701 EMBL ABZ85230.1
OrganismHeliobacterium modesticaldum (strain ATCC 51547 / Ice1) [Complete proteome] [HAMAP] EMBL ABZ85230.1
Taxonomic identifier498761 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesHeliobacteriaceaeHeliobacterium

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) By similarity. HAMAP-Rule MF_00244

Catalytic activity

ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD+. HAMAP-Rule MF_00244 SAAS SAAS005248

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1. HAMAP-Rule MF_00244

Sequence similarities

Belongs to the NadD family. HAMAP-Rule MF_00244

Sequences

Sequence LengthMass (Da)Tools
B0TBV7 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 17192F8591BEE002

FASTA21024,237
        10         20         30         40         50         60 
MVRVGIMGGT FDPVHYGHLV TAEAAADLFD LSVVVFVPSG RPPHKQHQDV TDPWERYRLT 

        70         80         90        100        110        120 
ELATCSNPRF RMSDVEVIRP GYSYTIDTVR AFRREYGEQA EFFFITGADA ILEIMTWRQI 

       130        140        150        160        170        180 
DQLMAECRFI AAYRPGYGRD HLRKAVARME AFSGRIHLVE VPALAISSTD IRRRLYEGRS 

       190        200        210 
VKYLLPEPVL HRIMETGVYH LASRHRQPRE 

« Hide

References

[1]"The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus."
Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M., Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W.
J. Bacteriol. 190:4687-4696(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51547 / Ice1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000930 Genomic DNA. Translation: ABZ85230.1.
RefSeqYP_001681241.1. NC_010337.2.

3D structure databases

ProteinModelPortalB0TBV7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING498761.HM1_2701.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABZ85230; ABZ85230; HM1_2701.
GeneID5909809.
KEGGhmo:HM1_2701.
PATRIC22109437. VBIHelMod36755_2422.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1057.
HOGENOMHOG000262779.
KOK00969.
OMAHYGHLRP.
OrthoDBEOG6F55KJ.

Enzyme and pathway databases

BioCycHMOD498761:GI46-2716-MONOMER.
UniPathwayUPA00253; UER00332.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00244. NaMN_adenylyltr.
InterProIPR004821. Cyt_trans-like.
IPR005248. NAMN_adtrnsfrase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR12039. PTHR12039. 1 hit.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
TIGR00482. TIGR00482. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB0TBV7_HELMI
AccessionPrimary (citable) accession number: B0TBV7
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)