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B0TBA1 (B0TBA1_HELMI) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribose-phosphate pyrophosphokinase HAMAP-Rule MF_00583
Short name=RPPK HAMAP-Rule MF_00583
EC=2.7.6.1 HAMAP-Rule MF_00583
Alternative name(s):
Phosphoribosyl pyrophosphate synthase HAMAP-Rule MF_00583
Gene names
Name:prs HAMAP-Rule MF_00583
Ordered Locus Names:Helmi_12030
ORF Names:HM1_0727 EMBL ABZ83828.1
OrganismHeliobacterium modesticaldum (strain ATCC 51547 / Ice1) [Complete proteome] [HAMAP] EMBL ABZ83828.1
Taxonomic identifier498761 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Heliobacteriaceae › Heliobacterium ›

Protein attributes

Sequence length315 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00583 RuleBase RU004325

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_00583

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. HAMAP-Rule MF_00583

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00583.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family. HAMAP-Rule MF_00583 RuleBase RU004324

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region215 – 228145-phosphoribose 1-diphosphate binding By similarity HAMAP-Rule MF_00583

Sites

Metal binding1321Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1341Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1431Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1471Magnesium By similarity HAMAP-Rule MF_00583

Sequences

Sequence LengthMass (Da)Tools
B0TBA1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: ED4874C61F389C2C

FASTA31534,288
        10         20         30         40         50         60 
MSFFNKKLKI FTGNANPALA EEIAEYLGVQ VGAAKVKSFS DGEIQMEIDE SVRGADVFVV 

        70         80         90        100        110        120 
QPTCYPVNEN IMELLIMVDA LRRASARRIT AVLPYYGYAR QDRKVRARAP ISAKLVANIL 

       130        140        150        160        170        180 
TAAGARRVVT MDLHAGQIQG FFDIPVDHLP GVPILAEYFL NKGLQDIVVV SPDLGGVTRA 

       190        200        210        220        230        240 
RDLAERIGAS LAIIDKRRPE PNVSEVMNVI GDIEGKTVVI TDDIIDTAGT IVNGAKALLE 

       250        260        270        280        290        300 
RGAREVYTCA THGVLSGPAI ERIQNSPIKE MILTNTIPLP PEKQIDKIRV LSVAPLLGEA 

       310 
IIRIHEDLSV SKLFD

« Hide

References

[1]"The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus."
Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M., Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W.
J. Bacteriol. 190:4687-4696(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51547 / Ice1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000930 Genomic DNA. Translation: ABZ83828.1.
RefSeqYP_001679839.1. NC_010337.2.

3D structure databases

ProteinModelPortalB0TBA1.
SMRB0TBA1. Positions 5-314.
ModBaseSearch...

Protein-protein interaction databases

STRING498761.HM1_0727.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABZ83828; ABZ83828; HM1_0727.
GeneID5912034.
KEGGhmo:HM1_0727.
PATRIC22106663. VBIHelMod36755_1114.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0462.
HOGENOMHOG000210452.
KOK00948.
OMAYVQIQES.
ProtClustDBCLSK941301.

Enzyme and pathway databases

BioCycHMOD498761:GI46-605-MONOMER.
UniPathwayUPA00087; UER00172.

Family and domain databases

HAMAPMF_00583_B. RibP_PPkinase_B.
InterProIPR000842. PRib_PP_synth_CS.
IPR000836. PRibTrfase_dom.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. ribP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0TBA1_HELMI
AccessionPrimary (citable) accession number: B0TBA1
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info